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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2B All Species: 44.24
Human Site: Y188 Identified Species: 81.11
UniProt: P67870 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P67870 NP_001311.3 215 24942 Y188 N Q F V P R L Y G F K I H P M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112540 234 26907 Y207 N Q F V P R L Y G F K I H P M
Dog Lupus familis XP_532075 304 34323 Y277 N Q F V P R L Y G F K I H P M
Cat Felis silvestris
Mouse Mus musculus NP_034105 215 24924 Y188 N Q F V P R L Y G F K I H P M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P28021 215 24942 Y188 N Q F V P R L Y G F K I H P M
Zebra Danio Brachydanio rerio Q91398 215 24867 Y188 N Q F V P R L Y G F K I H P M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08182 235 27069 Y188 N Q F V P R L Y G F K I H S L
Honey Bee Apis mellifera XP_624048 221 25542 Y188 N Q F V P R L Y G F K I H P L
Nematode Worm Caenorhab. elegans P28548 234 26417 Y187 T Q F V P K L Y G F K I H P V
Sea Urchin Strong. purpuratus XP_780696 223 25844 Y188 N Q F V P R L Y G F K I H P Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P40228 287 32336 T254 D G A Y F G T T F P H L F L M
Baker's Yeast Sacchar. cerevisiae P38930 258 29824 F218 K R Y V P K I F G F E L H K Q
Red Bread Mold Neurospora crassa Q8TG11 285 32554 Y192 E R Y I P R C Y G F K V H A A
Conservation
Percent
Protein Identity: 100 N.A. 91.8 70.7 N.A. 100 N.A. N.A. N.A. N.A. 99.5 99 N.A. 81.6 86.4 71.3 84.7
Protein Similarity: 100 N.A. 91.8 70.7 N.A. 100 N.A. N.A. N.A. N.A. 100 99.5 N.A. 88 93.2 81.6 91
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 100 N.A. 86.6 93.3 80 93.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 100 N.A. 93.3 100 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 41.4 40.3 39.3
Protein Similarity: N.A. N.A. N.A. 50.8 55.8 54.3
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 46.6
P-Site Similarity: N.A. N.A. N.A. 20 80 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 77 0 8 0 0 8 8 93 0 0 8 0 0 % F
% Gly: 0 8 0 0 0 8 0 0 93 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 93 0 0 % H
% Ile: 0 0 0 8 0 0 8 0 0 0 0 77 0 0 0 % I
% Lys: 8 0 0 0 0 16 0 0 0 0 85 0 0 8 0 % K
% Leu: 0 0 0 0 0 0 77 0 0 0 0 16 0 8 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54 % M
% Asn: 70 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 93 0 0 0 0 8 0 0 0 70 0 % P
% Gln: 0 77 0 0 0 0 0 0 0 0 0 0 0 0 16 % Q
% Arg: 0 16 0 0 0 77 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % S
% Thr: 8 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % T
% Val: 0 0 0 85 0 0 0 0 0 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 16 8 0 0 0 85 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _