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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPM4 All Species: 45.15
Human Site: S170 Identified Species: 90.3
UniProt: P67936 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P67936 NP_001138632.1 248 28522 S170 N V T N N L K S L E A A S E K
Chimpanzee Pan troglodytes XP_516337 248 28597 S170 N V T N N L K S L E A A S E K
Rhesus Macaque Macaca mulatta XP_001092183 248 28486 S170 N V T N N L K S L E A A S E K
Dog Lupus familis XP_866095 279 31736 S201 N V T N N L K S L E A A S E K
Cat Felis silvestris
Mouse Mus musculus Q6IRU2 248 28449 S170 N V T N N L K S L E A A S E K
Rat Rattus norvegicus P09495 248 28491 S170 N V T N N L K S L E A A S E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P19352 284 32758 S206 I V T N N L K S L E A Q A D K
Frog Xenopus laevis Q01173 284 32632 S206 T V T N N L K S L E A Q A E K
Zebra Danio Brachydanio rerio P13104 284 32704 S206 T V T N N M K S L E A Q A E K
Tiger Blowfish Takifugu rubipres NP_001027743 248 28766 S170 T V T N N L K S L E A Q A E K
Fruit Fly Dros. melanogaster P06754 339 39307 S260 V V G N N L K S L E V S E E K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27249 256 29613 S178 V V G N N L K S L E V S E E K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 99.1 78.1 N.A. 95.9 97.9 N.A. N.A. 65.8 65.1 64.7 80.6 43.3 N.A. 51.9 N.A.
Protein Similarity: 100 97.5 99.5 82.8 N.A. 98.3 98.7 N.A. N.A. 76.7 77.4 76.7 91.5 56.6 N.A. 72.6 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 73.3 80 73.3 80 66.6 N.A. 66.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 86.6 86.6 86.6 73.3 N.A. 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 84 50 34 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 100 0 0 17 92 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 100 % K
% Leu: 0 0 0 0 0 92 0 0 100 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 50 0 0 100 100 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 34 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 17 50 0 0 % S
% Thr: 25 0 84 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 17 100 0 0 0 0 0 0 0 0 17 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _