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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPM4
All Species:
29.09
Human Site:
T241
Identified Species:
58.18
UniProt:
P67936
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P67936
NP_001138632.1
248
28522
T241
L
H
Q
T
L
D
Q
T
L
N
E
L
N
C
I
Chimpanzee
Pan troglodytes
XP_516337
248
28597
T241
L
H
Q
T
L
D
Q
T
L
N
K
L
N
C
I
Rhesus Macaque
Macaca mulatta
XP_001092183
248
28486
T241
L
H
Q
T
L
D
Q
T
L
N
E
L
N
C
I
Dog
Lupus familis
XP_866095
279
31736
T272
L
H
Q
T
L
D
Q
T
L
N
E
L
N
C
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6IRU2
248
28449
T241
L
H
Q
T
L
D
Q
T
L
N
E
L
N
C
I
Rat
Rattus norvegicus
P09495
248
28491
T241
L
H
Q
T
L
D
Q
T
L
N
E
L
N
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19352
284
32758
A277
I
S
E
E
L
D
N
A
L
N
D
I
T
S
L
Frog
Xenopus laevis
Q01173
284
32632
A277
I
S
E
E
L
D
H
A
L
N
D
M
T
S
I
Zebra Danio
Brachydanio rerio
P13104
284
32704
A277
I
S
E
E
L
D
H
A
L
N
D
M
T
S
I
Tiger Blowfish
Takifugu rubipres
NP_001027743
248
28766
T241
M
H
Q
M
M
D
Q
T
L
M
E
L
N
N
L
Fruit Fly
Dros. melanogaster
P06754
339
39307
A331
I
G
D
D
L
D
T
A
F
V
E
L
I
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
T249
L
T
E
E
I
E
Q
T
V
Q
E
I
Q
G
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
99.1
78.1
N.A.
95.9
97.9
N.A.
N.A.
65.8
65.1
64.7
80.6
43.3
N.A.
51.9
N.A.
Protein Similarity:
100
97.5
99.5
82.8
N.A.
98.3
98.7
N.A.
N.A.
76.7
77.4
76.7
91.5
56.6
N.A.
72.6
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
26.6
33.3
33.3
60
26.6
N.A.
26.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
60
60
60
80
33.3
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% C
% Asp:
0
0
9
9
0
92
0
0
0
0
25
0
0
0
0
% D
% Glu:
0
0
34
34
0
9
0
0
0
0
67
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
59
0
0
0
0
17
0
0
0
0
0
0
0
0
% H
% Ile:
34
0
0
0
9
0
0
0
0
0
0
17
9
0
67
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% K
% Leu:
59
0
0
0
84
0
0
0
84
0
0
67
0
9
17
% L
% Met:
9
0
0
9
9
0
0
0
0
9
0
17
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
75
0
0
59
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
59
0
0
0
67
0
0
9
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
25
0
0
0
0
0
0
0
0
0
0
0
25
9
% S
% Thr:
0
9
0
50
0
0
9
67
0
0
0
0
25
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _