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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPM4
All Species:
42.73
Human Site:
Y185
Identified Species:
85.45
UniProt:
P67936
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P67936
NP_001138632.1
248
28522
Y185
Y
S
E
K
E
D
K
Y
E
E
E
I
K
L
L
Chimpanzee
Pan troglodytes
XP_516337
248
28597
C185
Y
S
E
K
E
D
K
C
E
E
E
I
K
L
L
Rhesus Macaque
Macaca mulatta
XP_001092183
248
28486
Y185
Y
S
E
K
E
D
K
Y
E
E
E
I
K
L
L
Dog
Lupus familis
XP_866095
279
31736
Y216
Y
S
E
K
E
D
K
Y
E
E
E
I
K
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6IRU2
248
28449
Y185
Y
S
E
K
E
D
K
Y
E
E
E
I
K
L
L
Rat
Rattus norvegicus
P09495
248
28491
Y185
Y
S
E
K
E
D
K
Y
E
E
E
I
K
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19352
284
32758
Y221
Y
S
T
K
E
D
K
Y
E
E
E
I
K
L
L
Frog
Xenopus laevis
Q01173
284
32632
Y221
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
Zebra Danio
Brachydanio rerio
P13104
284
32704
Y221
Y
S
A
K
E
D
K
Y
E
E
E
I
K
V
L
Tiger Blowfish
Takifugu rubipres
NP_001027743
248
28766
Y185
Y
S
Q
K
E
D
K
Y
E
E
E
I
K
V
L
Fruit Fly
Dros. melanogaster
P06754
339
39307
Y275
A
N
Q
R
E
E
E
Y
K
N
Q
I
K
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
Y193
A
L
Q
R
E
D
S
Y
E
E
Q
I
R
T
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
99.1
78.1
N.A.
95.9
97.9
N.A.
N.A.
65.8
65.1
64.7
80.6
43.3
N.A.
51.9
N.A.
Protein Similarity:
100
97.5
99.5
82.8
N.A.
98.3
98.7
N.A.
N.A.
76.7
77.4
76.7
91.5
56.6
N.A.
72.6
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
86.6
86.6
33.3
N.A.
40
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
100
93.3
100
80
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
92
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
50
0
100
9
9
0
92
92
84
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% I
% Lys:
0
0
0
84
0
0
84
0
9
0
0
0
92
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
0
0
0
0
0
59
92
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
34
0
0
0
0
0
0
0
17
0
0
0
0
% Q
% Arg:
0
0
0
17
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
84
0
0
0
0
9
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
17
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
84
0
0
0
0
0
0
92
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _