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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUBA1B All Species: 54.24
Human Site: Y319 Identified Species: 99.44
UniProt: P68363 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P68363 NP_006073.2 451 50152 Y319 Y M A C C L L Y R G D V V P K
Chimpanzee Pan troglodytes Q5R1W4 451 50117 Y319 Y M A C C L L Y R G D V V P K
Rhesus Macaque Macaca mulatta XP_001108924 456 50752 Y324 Y M A C C L L Y R G D V V P K
Dog Lupus familis XP_851095 518 57415 Y386 Y M A C C L L Y R G D V V P K
Cat Felis silvestris
Mouse Mus musculus P05214 450 49941 Y319 Y M A C C M L Y R G D V V P K
Rat Rattus norvegicus Q6P9V9 451 50133 Y319 Y M A C C L L Y R G D V V P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510837 454 50448 Y322 Y M A C C L L Y R G D V V P K
Chicken Gallus gallus P09644 448 49930 Y319 Y M A C C L L Y R G D V V P K
Frog Xenopus laevis P08537 449 49861 Y319 Y M A C C L L Y R G D V V P K
Zebra Danio Brachydanio rerio NP_001098596 451 50133 Y319 Y M A C C L L Y R G D V V P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P06603 450 49890 Y319 Y M A C C M L Y R G D V V P K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34690 448 49895 Y317 Y M A V C L L Y R G D V V P K
Sea Urchin Strong. purpuratus XP_001178141 451 50085 Y319 Y M A C C M L Y R G D V V P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.4 87 N.A. 97.1 100 N.A. 98.9 95.1 97.7 99.3 N.A. 96.4 N.A. 88.2 97.7
Protein Similarity: 100 99.7 98.6 87 N.A. 98.6 100 N.A. 99.1 96.6 98.8 99.7 N.A. 98.6 N.A. 94.9 99.7
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 100 100 100 100 N.A. 93.3 N.A. 93.3 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 N.A. 93.3 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 93 100 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % K
% Leu: 0 0 0 0 0 77 100 0 0 0 0 0 0 0 0 % L
% Met: 0 100 0 0 0 24 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 100 100 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 100 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _