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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK2A1
All Species:
37.58
Human Site:
S287
Identified Species:
51.67
UniProt:
P68400
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P68400
NP_001886.1
391
45144
S287
R
W
E
R
F
V
H
S
E
N
Q
H
L
V
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112211
397
46613
S287
R
W
E
R
F
V
H
S
E
N
Q
H
L
V
S
Dog
Lupus familis
XP_534375
403
46681
S287
R
W
E
R
F
V
H
S
E
N
Q
H
L
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60737
391
45143
S287
R
W
E
R
F
V
H
S
E
N
Q
H
L
V
S
Rat
Rattus norvegicus
P19139
391
45055
S287
R
W
E
R
F
V
H
S
E
N
Q
H
L
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507666
350
41142
K260
D
E
L
Y
G
Y
L
K
K
Y
H
I
D
L
D
Chicken
Gallus gallus
P21868
391
45172
S287
R
W
E
R
F
V
H
S
E
N
Q
H
L
V
S
Frog
Xenopus laevis
P28020
392
45169
S287
R
W
E
R
F
V
H
S
E
N
Q
H
L
V
S
Zebra Danio
Brachydanio rerio
NP_001002164
393
45422
S287
R
W
E
R
F
V
H
S
E
N
Q
H
L
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08181
336
39941
V246
Q
L
V
R
I
A
K
V
L
G
T
E
E
L
Y
Honey Bee
Apis mellifera
XP_393260
350
41645
Y255
G
T
E
E
L
F
E
Y
L
E
K
Y
H
I
E
Nematode Worm
Caenorhab. elegans
P18334
360
42239
N269
I
D
L
D
P
R
F
N
D
I
L
G
R
H
S
Sea Urchin
Strong. purpuratus
XP_785475
398
46271
S285
R
W
E
R
F
V
H
S
E
N
Q
H
L
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P28523
332
39212
K242
D
Q
L
V
K
I
A
K
V
L
G
T
D
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q08467
333
39240
V243
Q
L
V
K
I
A
K
V
L
G
T
D
E
L
N
Baker's Yeast
Sacchar. cerevisiae
P19454
339
39385
N249
P
F
F
K
G
S
S
N
P
D
Q
L
V
K
I
Red Bread Mold
Neurospora crassa
Q8TG13
336
39621
E246
A
K
V
L
G
T
D
E
L
F
D
Y
L
D
K
Conservation
Percent
Protein Identity:
100
N.A.
90.4
97
N.A.
97.4
98.4
N.A.
75.4
97.9
94.9
89
N.A.
75.9
79.5
72.8
78.3
Protein Similarity:
100
N.A.
92.1
97
N.A.
98.7
98.9
N.A.
82.6
98.9
97.1
93.8
N.A.
81.8
86.1
82.3
87.1
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
6.6
6.6
6.6
100
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
20
26.6
20
100
Percent
Protein Identity:
N.A.
65.2
N.A.
63.4
49.8
61.1
Protein Similarity:
N.A.
74.9
N.A.
75.4
63.6
72.8
P-Site Identity:
N.A.
0
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
6.6
N.A.
26.6
40
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
12
6
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
6
0
6
0
0
6
0
6
6
6
6
12
6
6
% D
% Glu:
0
6
59
6
0
0
6
6
53
6
0
6
12
0
6
% E
% Phe:
0
6
6
0
53
6
6
0
0
6
0
0
0
0
0
% F
% Gly:
6
0
0
0
18
0
0
0
0
12
6
6
0
6
0
% G
% His:
0
0
0
0
0
0
53
0
0
0
6
53
6
6
0
% H
% Ile:
6
0
0
0
12
6
0
0
0
6
0
6
0
6
6
% I
% Lys:
0
6
0
12
6
0
12
12
6
0
6
0
0
6
6
% K
% Leu:
0
12
18
6
6
0
6
0
24
6
6
6
59
18
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
53
0
0
0
0
6
% N
% Pro:
6
0
0
0
6
0
0
0
6
0
0
0
0
0
0
% P
% Gln:
12
6
0
0
0
0
0
0
0
0
59
0
0
0
0
% Q
% Arg:
53
0
0
59
0
6
0
0
0
0
0
0
6
0
0
% R
% Ser:
0
0
0
0
0
6
6
53
0
0
0
0
0
0
59
% S
% Thr:
0
6
0
0
0
6
0
0
0
0
12
6
0
0
0
% T
% Val:
0
0
18
6
0
53
0
12
6
0
0
0
6
53
0
% V
% Trp:
0
53
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
6
0
6
0
6
0
12
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _