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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A1 All Species: 16.67
Human Site: S338 Identified Species: 22.92
UniProt: P68400 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P68400 NP_001886.1 391 45144 S338 Q A R M G S S S M P G G S T P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112211 397 46613 S338 Q A R M G S S S M P G G S T P
Dog Lupus familis XP_534375 403 46681 S338 Q A R M G S S S M P G G S T P
Cat Felis silvestris
Mouse Mus musculus Q60737 391 45143 S338 Q A R M S S T S M A G G S T P
Rat Rattus norvegicus P19139 391 45055 G338 Q A R M S S A G M A G G S T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 Q311 K L L R Y D H Q Q R L T A K E
Chicken Gallus gallus P21868 391 45172 N338 Q A R M G S S N M P G G S T P
Frog Xenopus laevis P28020 392 45169 N338 Q S R M G G S N M P S G S S T
Zebra Danio Brachydanio rerio NP_001002164 393 45422 S338 Q A R M G S T S G L S T G S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 D297 L V S P E A L D F L D K L L R
Honey Bee Apis mellifera XP_393260 350 41645 D306 L D K L L R Y D H Y E R L T A
Nematode Worm Caenorhab. elegans P18334 360 42239 H320 T A Q E A M G H E Y F R P V V
Sea Urchin Strong. purpuratus XP_785475 398 46271 V336 Q N R S M P P V M S T Q P N T
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 I293 H L V S P E A I D F L D K L L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08467 333 39240 D294 L V S P E A I D F L D K L L R
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 T300 T H F I T S E T K L A V P E V
Red Bread Mold Neurospora crassa Q8TG13 336 39621 L297 A I D F L D K L L R Y D H N E
Conservation
Percent
Protein Identity: 100 N.A. 90.4 97 N.A. 97.4 98.4 N.A. 75.4 97.9 94.9 89 N.A. 75.9 79.5 72.8 78.3
Protein Similarity: 100 N.A. 92.1 97 N.A. 98.7 98.9 N.A. 82.6 98.9 97.1 93.8 N.A. 81.8 86.1 82.3 87.1
P-Site Identity: 100 N.A. 100 100 N.A. 80 73.3 N.A. 0 93.3 60 46.6 N.A. 0 6.6 6.6 20
P-Site Similarity: 100 N.A. 100 100 N.A. 86.6 80 N.A. 13.3 100 80 60 N.A. 6.6 20 13.3 20
Percent
Protein Identity: N.A. 65.2 N.A. 63.4 49.8 61.1
Protein Similarity: N.A. 74.9 N.A. 75.4 63.6 72.8
P-Site Identity: N.A. 0 N.A. 0 6.6 0
P-Site Similarity: N.A. 6.6 N.A. 6.6 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 48 0 0 6 12 12 0 0 12 6 0 6 0 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 6 0 0 12 0 18 6 0 12 12 0 0 0 % D
% Glu: 0 0 0 6 12 6 6 0 6 0 6 0 0 6 12 % E
% Phe: 0 0 6 6 0 0 0 0 12 6 6 0 0 0 0 % F
% Gly: 0 0 0 0 36 6 6 6 6 0 36 42 6 0 0 % G
% His: 6 6 0 0 0 0 6 6 6 0 0 0 6 0 0 % H
% Ile: 0 6 0 6 0 0 6 6 0 0 0 0 0 0 0 % I
% Lys: 6 0 6 0 0 0 6 0 6 0 0 12 6 6 0 % K
% Leu: 18 12 6 6 12 0 6 6 6 24 12 0 18 18 6 % L
% Met: 0 0 0 48 6 6 0 0 48 0 0 0 0 0 0 % M
% Asn: 0 6 0 0 0 0 0 12 0 0 0 0 0 12 0 % N
% Pro: 0 0 0 12 6 6 6 0 0 30 0 0 18 0 36 % P
% Gln: 53 0 6 0 0 0 0 6 6 0 0 6 0 0 0 % Q
% Arg: 0 0 53 6 0 6 0 0 0 12 0 12 0 0 12 % R
% Ser: 0 6 12 12 12 48 30 30 0 6 12 0 42 12 0 % S
% Thr: 12 0 0 0 6 0 12 6 0 0 6 12 0 42 18 % T
% Val: 0 12 6 0 0 0 0 6 0 0 0 6 0 6 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 6 0 0 12 6 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _