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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A1 All Species: 18.18
Human Site: S370 Identified Species: 25
UniProt: P68400 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P68400 NP_001886.1 391 45144 S370 P L G P L A G S P V I A A A N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112211 397 46613 S370 A G L E L L S S T S Q P A L T
Dog Lupus familis XP_534375 403 46681 V370 E K S R I S S V P T P S P L G
Cat Felis silvestris
Mouse Mus musculus Q60737 391 45143 S370 P L G P L A G S P V I A A A N
Rat Rattus norvegicus P19139 391 45055 S370 P L G P L A G S P V I A A A N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 S343 S S D N A V L S S G L T A A R
Chicken Gallus gallus P21868 391 45172 S370 P L G P L A G S P V I S A T T
Frog Xenopus laevis P28020 392 45169 G370 S A L G S L A G S P V I S A T
Zebra Danio Brachydanio rerio NP_001002164 393 45422 A370 S Q P M A N M A G S P V I S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 Q329 F L P I V N G Q M N P N N Q Q
Honey Bee Apis mellifera XP_393260 350 41645 S338 R L N M V S S S P T P I T G S
Nematode Worm Caenorhab. elegans P18334 360 42239 S352 S N S A S S Q S S D A K I D G
Sea Urchin Strong. purpuratus XP_785475 398 46271 G368 D T K A R P S G T I P G A P L
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 A325 Y F Q Q V R A A E N S R T R A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08467 333 39240 E326 F A Q V R A A E T S R M R S Q
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 K332 A K E A M D H K F F K T K F E
Red Bread Mold Neurospora crassa Q8TG13 336 39621 Y329 D E A T R A R Y L A G E T I N
Conservation
Percent
Protein Identity: 100 N.A. 90.4 97 N.A. 97.4 98.4 N.A. 75.4 97.9 94.9 89 N.A. 75.9 79.5 72.8 78.3
Protein Similarity: 100 N.A. 92.1 97 N.A. 98.7 98.9 N.A. 82.6 98.9 97.1 93.8 N.A. 81.8 86.1 82.3 87.1
P-Site Identity: 100 N.A. 20 6.6 N.A. 100 100 N.A. 20 80 6.6 0 N.A. 13.3 20 6.6 6.6
P-Site Similarity: 100 N.A. 20 26.6 N.A. 100 100 N.A. 26.6 86.6 20 20 N.A. 20 40 13.3 13.3
Percent
Protein Identity: N.A. 65.2 N.A. 63.4 49.8 61.1
Protein Similarity: N.A. 74.9 N.A. 75.4 63.6 72.8
P-Site Identity: N.A. 0 N.A. 6.6 0 13.3
P-Site Similarity: N.A. 13.3 N.A. 13.3 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 6 18 12 36 18 12 0 6 6 18 42 30 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 6 0 0 6 0 0 0 6 0 0 0 6 0 % D
% Glu: 6 6 6 6 0 0 0 6 6 0 0 6 0 0 6 % E
% Phe: 12 6 0 0 0 0 0 0 6 6 0 0 0 6 0 % F
% Gly: 0 6 24 6 0 0 30 12 6 6 6 6 0 6 12 % G
% His: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 6 6 0 0 0 0 6 24 12 12 6 0 % I
% Lys: 0 12 6 0 0 0 0 6 0 0 6 6 6 0 0 % K
% Leu: 0 36 12 0 30 12 6 0 6 0 6 0 0 12 6 % L
% Met: 0 0 0 12 6 0 6 0 6 0 0 6 0 0 0 % M
% Asn: 0 6 6 6 0 12 0 0 0 12 0 6 6 0 24 % N
% Pro: 24 0 12 24 0 6 0 0 36 6 30 6 6 6 0 % P
% Gln: 0 6 12 6 0 0 6 6 0 0 6 0 0 6 12 % Q
% Arg: 6 0 0 6 18 6 6 0 0 0 6 6 6 6 6 % R
% Ser: 24 6 12 0 12 18 24 48 18 18 6 12 6 12 12 % S
% Thr: 0 6 0 6 0 0 0 0 18 12 0 12 18 6 18 % T
% Val: 0 0 0 6 18 6 0 6 0 24 6 6 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _