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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A1 All Species: 40
Human Site: Y12 Identified Species: 55
UniProt: P68400 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P68400 NP_001886.1 391 45144 Y12 V P S R A R V Y T D V N T H R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112211 397 46613 Y12 V P S R A R V Y T D V N T H R
Dog Lupus familis XP_534375 403 46681 Y12 V P S R A R V Y T D V N T H R
Cat Felis silvestris
Mouse Mus musculus Q60737 391 45143 Y12 V P S R A R V Y T D V N T H R
Rat Rattus norvegicus P19139 391 45055 Y12 V P S R A R V Y T D V N T H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 Y13 A G S R A R V Y A E V N S L R
Chicken Gallus gallus P21868 391 45172 Y12 V P S R A R V Y T D V N T H R
Frog Xenopus laevis P28020 392 45169 Y12 V P S R A R V Y T D V N T H R
Zebra Danio Brachydanio rerio NP_001002164 393 45422 Y12 V T S R S R V Y P D V N T Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 T11 P S A A R V Y T D V N A H K P
Honey Bee Apis mellifera XP_393260 350 41645 D12 S R A R V Y T D V N S H K S R
Nematode Worm Caenorhab. elegans P18334 360 42239 Y22 N P S R P R E Y W D Y E A H M
Sea Urchin Strong. purpuratus XP_785475 398 46271 Y21 N S H R P R E Y W D Y E S H V
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08467 333 39240 T8 M S K A R V Y T E V N V I R P
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 S12 P S T L N Q K S N R V Y S V A
Red Bread Mold Neurospora crassa Q8TG13 336 39621 N11 V Y A D V N Q N M P R A Y W D
Conservation
Percent
Protein Identity: 100 N.A. 90.4 97 N.A. 97.4 98.4 N.A. 75.4 97.9 94.9 89 N.A. 75.9 79.5 72.8 78.3
Protein Similarity: 100 N.A. 92.1 97 N.A. 98.7 98.9 N.A. 82.6 98.9 97.1 93.8 N.A. 81.8 86.1 82.3 87.1
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 60 100 100 73.3 N.A. 0 13.3 46.6 33.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 73.3 100 100 80 N.A. 6.6 33.3 46.6 40
Percent
Protein Identity: N.A. 65.2 N.A. 63.4 49.8 61.1
Protein Similarity: N.A. 74.9 N.A. 75.4 63.6 72.8
P-Site Identity: N.A. 0 N.A. 0 6.6 6.6
P-Site Similarity: N.A. 0 N.A. 6.6 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 18 12 48 0 0 0 6 0 0 12 6 0 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 6 0 0 0 6 6 59 0 0 0 0 6 % D
% Glu: 0 0 0 0 0 0 12 0 6 6 0 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 6 0 0 0 0 0 0 0 0 6 6 53 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % I
% Lys: 0 0 6 0 0 0 6 0 0 0 0 0 6 6 0 % K
% Leu: 0 0 0 6 0 0 0 0 0 0 0 0 0 6 0 % L
% Met: 6 0 0 0 0 0 0 0 6 0 0 0 0 0 6 % M
% Asn: 12 0 0 0 6 6 0 6 6 6 12 53 0 0 0 % N
% Pro: 12 48 0 0 12 0 0 0 6 6 0 0 0 0 12 % P
% Gln: 0 0 0 0 0 6 6 0 0 0 0 0 0 6 0 % Q
% Arg: 0 6 0 71 12 65 0 0 0 6 6 0 0 6 59 % R
% Ser: 6 24 59 0 6 0 0 6 0 0 6 0 18 6 0 % S
% Thr: 0 6 6 0 0 0 6 12 42 0 0 0 48 0 0 % T
% Val: 53 0 0 0 12 12 53 0 6 12 59 6 0 6 6 % V
% Trp: 0 0 0 0 0 0 0 0 12 0 0 0 0 6 0 % W
% Tyr: 0 6 0 0 0 6 12 65 0 0 12 6 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _