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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A1 All Species: 38.79
Human Site: Y23 Identified Species: 53.33
UniProt: P68400 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P68400 NP_001886.1 391 45144 Y23 N T H R P R E Y W D Y E S H V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112211 397 46613 Y23 N T H R P R E Y W D Y E S H V
Dog Lupus familis XP_534375 403 46681 Y23 N T H R P R E Y W D Y E S H V
Cat Felis silvestris
Mouse Mus musculus Q60737 391 45143 Y23 N T H R P R E Y W D Y E S H V
Rat Rattus norvegicus P19139 391 45055 Y23 N T H R P R E Y W D Y E S H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 Y24 N S L R S R D Y W D Y E A H V
Chicken Gallus gallus P21868 391 45172 Y23 N T H R P R E Y W D Y E S H V
Frog Xenopus laevis P28020 392 45169 Y23 N T H R P R D Y W D Y E S H V
Zebra Danio Brachydanio rerio NP_001002164 393 45422 Y23 N T Q R P R E Y W D Y E S H V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 W22 A H K P D E Y W D Y E N Y V V
Honey Bee Apis mellifera XP_393260 350 41645 D23 H K S R D Y W D Y E S Y V V D
Nematode Worm Caenorhab. elegans P18334 360 42239 G33 E A H M I E W G Q I D D Y Q L
Sea Urchin Strong. purpuratus XP_785475 398 46271 G32 E S H V V E W G Q Q D D Y Q I
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 Y18 N V L R P K E Y W D Y E A L T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08467 333 39240 W19 V I R P K D Y W D Y E S L I V
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 K23 Y S V A R V Y K N A C E E R P
Red Bread Mold Neurospora crassa Q8TG13 336 39621 V22 A Y W D Y D S V N I S W G V L
Conservation
Percent
Protein Identity: 100 N.A. 90.4 97 N.A. 97.4 98.4 N.A. 75.4 97.9 94.9 89 N.A. 75.9 79.5 72.8 78.3
Protein Similarity: 100 N.A. 92.1 97 N.A. 98.7 98.9 N.A. 82.6 98.9 97.1 93.8 N.A. 81.8 86.1 82.3 87.1
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 66.6 100 93.3 93.3 N.A. 6.6 6.6 6.6 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 86.6 100 100 93.3 N.A. 13.3 26.6 20 26.6
Percent
Protein Identity: N.A. 65.2 N.A. 63.4 49.8 61.1
Protein Similarity: N.A. 74.9 N.A. 75.4 63.6 72.8
P-Site Identity: N.A. 60 N.A. 6.6 6.6 0
P-Site Similarity: N.A. 73.3 N.A. 13.3 13.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 6 0 6 0 0 0 0 0 6 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % C
% Asp: 0 0 0 6 12 12 12 6 12 59 12 12 0 0 6 % D
% Glu: 12 0 0 0 0 18 48 0 0 6 12 65 6 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 12 0 0 0 0 6 0 0 % G
% His: 6 6 53 0 0 0 0 0 0 0 0 0 0 53 0 % H
% Ile: 0 6 0 0 6 0 0 0 0 12 0 0 0 6 6 % I
% Lys: 0 6 6 0 6 6 0 6 0 0 0 0 0 0 0 % K
% Leu: 0 0 12 0 0 0 0 0 0 0 0 0 6 6 12 % L
% Met: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 59 0 0 0 0 0 0 0 12 0 0 6 0 0 0 % N
% Pro: 0 0 0 12 53 0 0 0 0 0 0 0 0 0 6 % P
% Gln: 0 0 6 0 0 0 0 0 12 6 0 0 0 12 0 % Q
% Arg: 0 0 6 65 6 53 0 0 0 0 0 0 0 6 0 % R
% Ser: 0 18 6 0 6 0 6 0 0 0 12 6 48 0 0 % S
% Thr: 0 48 0 0 0 0 0 0 0 0 0 0 0 0 6 % T
% Val: 6 6 6 6 6 6 0 6 0 0 0 0 6 18 65 % V
% Trp: 0 0 6 0 0 0 18 12 59 0 0 6 0 0 0 % W
% Tyr: 6 6 0 0 6 6 18 59 6 12 59 6 18 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _