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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF4
All Species:
22.42
Human Site:
T110
Identified Species:
44.85
UniProt:
P78317
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78317
NP_002929.1
190
21319
T110
D
R
D
V
Y
V
T
T
H
T
P
R
N
A
R
Chimpanzee
Pan troglodytes
XP_001150084
190
21393
T110
D
R
D
V
Y
V
T
T
H
T
S
R
N
A
R
Rhesus Macaque
Macaca mulatta
XP_001118472
214
23910
T134
D
R
D
V
Y
V
T
T
H
T
P
R
N
T
R
Dog
Lupus familis
XP_853173
190
21359
T110
D
R
D
V
Y
V
T
T
H
T
P
R
N
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZS2
194
21892
T114
D
K
D
V
Y
V
T
T
H
T
P
R
S
T
K
Rat
Rattus norvegicus
O88846
194
21878
T114
D
K
D
V
Y
V
T
T
H
T
P
R
S
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516738
143
15737
H64
P
V
V
V
D
L
T
H
N
D
S
V
V
I
V
Chicken
Gallus gallus
NP_001012907
194
21547
V114
D
V
Y
V
T
D
K
V
S
R
E
L
G
P
L
Frog
Xenopus laevis
NP_001088681
190
20752
A110
S
R
D
T
E
L
F
A
T
N
K
D
I
S
S
Zebra Danio
Brachydanio rerio
XP_683428
184
20440
S104
E
E
S
S
L
R
L
S
P
G
L
L
S
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731017
312
34397
V232
R
S
A
E
N
D
P
V
V
D
L
D
V
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187376
182
20072
V102
R
R
S
D
Q
T
S
V
D
S
V
E
L
N
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
87.3
93.6
N.A.
89.6
91.2
N.A.
47.8
67.5
57.8
47.3
N.A.
24.3
N.A.
N.A.
N.A.
Protein Similarity:
100
95.7
87.3
96.8
N.A.
93.3
94.3
N.A.
57.8
80.9
73.1
64.7
N.A.
39.4
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
73.3
73.3
N.A.
13.3
13.3
13.3
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
26.6
13.3
26.6
26.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
9
0
0
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
59
0
59
9
9
17
0
0
9
17
0
17
0
0
0
% D
% Glu:
9
9
0
9
9
0
0
0
0
0
9
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
9
50
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% I
% Lys:
0
17
0
0
0
0
9
0
0
0
9
0
0
0
25
% K
% Leu:
0
0
0
0
9
17
9
0
0
0
17
17
9
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
9
9
0
0
34
9
0
% N
% Pro:
9
0
0
0
0
0
9
0
9
0
42
0
0
9
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
17
50
0
0
0
9
0
0
0
9
0
50
0
0
34
% R
% Ser:
9
9
17
9
0
0
9
9
9
9
17
0
25
17
17
% S
% Thr:
0
0
0
9
9
9
59
50
9
50
0
0
0
34
0
% T
% Val:
0
17
9
67
0
50
0
25
9
0
9
9
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
50
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _