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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IGBP1 All Species: 18.18
Human Site: S228 Identified Species: 36.36
UniProt: P78318 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78318 NP_001542.1 339 39222 S228 R D S S R E A S T S N S S R Q
Chimpanzee Pan troglodytes XP_523812 340 39080 S230 K D S S R E A S T S N S C H Q
Rhesus Macaque Macaca mulatta XP_001083069 339 39174 S228 R D S S R E A S T S N S S R Q
Dog Lupus familis XP_848610 340 39268 S229 K D S S K E E S T S Y S S H Q
Cat Felis silvestris
Mouse Mus musculus Q61249 340 38952 T229 K D S P R E E T A C H S S L P
Rat Rattus norvegicus O08836 340 39117 S229 K D S P R E E S A C Q S S L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001084735 340 38855 A232 R E A I K K G A E I P H H S R
Zebra Danio Brachydanio rerio NP_998687 355 40611 A246 M E L F K Q S A P Q P S P P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_723811 380 43301 H260 H S H G P G H H H H H Q Q A A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785736 351 40412 E227 M A K M K K T E N Q R P G E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LDQ4 405 45645 D228 I K E R Q L K D G E G G F S R
Baker's Yeast Sacchar. cerevisiae Q04372 366 42549 S236 L S N F L K N S V H E V K S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.4 97.3 84.7 N.A. 80.5 81.4 N.A. N.A. N.A. 57 51.8 N.A. 32.1 N.A. N.A. 36.4
Protein Similarity: 100 92 98.2 93.5 N.A. 92 91.7 N.A. N.A. N.A. 73.8 72.3 N.A. 50.7 N.A. N.A. 60.1
P-Site Identity: 100 80 100 66.6 N.A. 40 46.6 N.A. N.A. N.A. 6.6 6.6 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 86.6 100 80 N.A. 60 53.3 N.A. N.A. N.A. 46.6 46.6 N.A. 6.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 26.1 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. 48.6 47.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 0 25 17 17 0 0 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 17 0 0 9 0 0 % C
% Asp: 0 50 0 0 0 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 17 9 0 0 50 25 9 9 9 9 0 0 9 9 % E
% Phe: 0 0 0 17 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 9 0 9 9 0 9 0 9 9 9 0 0 % G
% His: 9 0 9 0 0 0 9 9 9 17 17 9 9 17 0 % H
% Ile: 9 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 34 9 9 0 34 25 9 0 0 0 0 0 9 0 9 % K
% Leu: 9 0 9 0 9 9 0 0 0 0 0 0 0 17 0 % L
% Met: 17 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 9 0 9 0 25 0 0 0 0 % N
% Pro: 0 0 0 17 9 0 0 0 9 0 17 9 9 9 17 % P
% Gln: 0 0 0 0 9 9 0 0 0 17 9 9 9 0 34 % Q
% Arg: 25 0 0 9 42 0 0 0 0 0 9 0 0 17 17 % R
% Ser: 0 17 50 34 0 0 9 50 0 34 0 59 42 25 9 % S
% Thr: 0 0 0 0 0 0 9 9 34 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _