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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM8
All Species:
4.85
Human Site:
T730
Identified Species:
11.85
UniProt:
P78325
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78325
NP_001100
824
88673
T730
P
Q
E
L
V
P
T
T
H
P
G
Q
P
A
R
Chimpanzee
Pan troglodytes
XP_519663
776
87192
T705
K
D
Q
R
P
L
S
T
T
G
T
R
P
H
K
Rhesus Macaque
Macaca mulatta
XP_001106707
776
87167
G707
Q
R
P
L
S
T
T
G
T
R
P
H
K
Q
K
Dog
Lupus familis
XP_548820
902
96081
M694
P
C
Q
P
A
R
P
M
A
S
T
A
T
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q05910
826
90028
R735
V
S
T
N
Q
P
P
R
P
I
V
K
P
K
R
Rat
Rattus norvegicus
Q9QYV0
816
88034
Q729
R
L
H
Q
R
L
C
Q
L
K
G
S
S
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507222
856
93750
S754
S
I
R
R
D
V
R
S
S
P
G
S
S
P
R
Chicken
Gallus gallus
NP_001136322
922
101009
R804
Q
K
R
D
G
P
R
R
P
L
P
Y
Q
I
V
Frog
Xenopus laevis
NP_001080914
914
99731
S773
S
T
S
K
E
T
R
S
R
D
I
F
Q
G
K
Zebra Danio
Brachydanio rerio
NP_956931
843
93452
T731
T
F
L
E
S
S
A
T
Q
A
C
K
P
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.1
37.5
36.4
N.A.
61.9
36.5
N.A.
38
36.4
35.3
39.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
51.9
51.7
47.3
N.A.
73.2
50.9
N.A.
53.3
51.5
50.5
56.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
6.6
N.A.
20
6.6
N.A.
20
6.6
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
26.6
20
N.A.
26.6
13.3
N.A.
26.6
13.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
10
10
0
10
0
10
0
% A
% Cys:
0
10
0
0
0
0
10
0
0
0
10
0
0
10
0
% C
% Asp:
0
10
0
10
10
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
0
10
30
0
0
10
0
% G
% His:
0
0
10
0
0
0
0
0
10
0
0
10
0
10
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
10
10
0
0
10
0
% I
% Lys:
10
10
0
10
0
0
0
0
0
10
0
20
10
10
40
% K
% Leu:
0
10
10
20
0
20
0
0
10
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
20
0
10
10
10
30
20
0
20
20
20
0
40
20
0
% P
% Gln:
20
10
20
10
10
0
0
10
10
0
0
10
20
10
10
% Q
% Arg:
10
10
20
20
10
10
30
20
10
10
0
10
0
0
40
% R
% Ser:
20
10
10
0
20
10
10
20
10
10
0
20
20
0
0
% S
% Thr:
10
10
10
0
0
20
20
30
20
0
20
0
10
0
0
% T
% Val:
10
0
0
0
10
10
0
0
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _