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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPC5 All Species: 20.61
Human Site: S186 Identified Species: 41.21
UniProt: P78333 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78333 NP_004457.1 572 63707 S186 I N P G V T D S S L E Y S E C
Chimpanzee Pan troglodytes A5A6P7 580 65546 S190 M N P G L P D S A L D I N E C
Rhesus Macaque Macaca mulatta XP_001097558 580 65585 S190 M N P G L P D S A L D I N E C
Dog Lupus familis XP_542637 1141 126362 S722 I N P G V T D S S L E Y S E C
Cat Felis silvestris
Mouse Mus musculus Q8CAL5 572 63773 S186 I N P G V T D S S L Q Y S E C
Rat Rattus norvegicus P13265 597 67030 S189 M N P G L P E S V L D I N E C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512016 621 68630 I268 I H P G S T D I T L E Y S E C
Chicken Gallus gallus P50593 550 61065 I181 L M N A Q Y H I T D E Y L D C
Frog Xenopus laevis NP_001084188 556 63021 F182 L V N P Q Y Q F T D E Y L E C
Zebra Danio Brachydanio rerio XP_001920549 337 37530 K18 L G F R S E M K H H R G P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24114 626 69013 L237 S K N N L G D L H E D Y V N C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001138966 605 67526 L185 I N S K V T R L D S R Y R D C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42 42.2 36.4 N.A. 85.6 41.2 N.A. 62.6 23.6 27.1 26.2 N.A. 26.6 N.A. N.A. 27.6
Protein Similarity: 100 60.6 60.8 41.1 N.A. 92.8 60.2 N.A. 74.4 47.5 50.7 40.5 N.A. 44.2 N.A. N.A. 46.7
P-Site Identity: 100 53.3 53.3 100 N.A. 93.3 46.6 N.A. 73.3 20 26.6 0 N.A. 20 N.A. N.A. 40
P-Site Similarity: 100 86.6 86.6 100 N.A. 100 80 N.A. 86.6 40 40 6.6 N.A. 33.3 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 17 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92 % C
% Asp: 0 0 0 0 0 0 59 0 9 17 34 0 0 17 0 % D
% Glu: 0 0 0 0 0 9 9 0 0 9 42 0 0 67 0 % E
% Phe: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 59 0 9 0 0 0 0 0 9 0 0 0 % G
% His: 0 9 0 0 0 0 9 0 17 9 0 0 0 0 0 % H
% Ile: 42 0 0 0 0 0 0 17 0 0 0 25 0 0 0 % I
% Lys: 0 9 0 9 0 0 0 9 0 0 0 0 0 0 0 % K
% Leu: 25 0 0 0 34 0 0 17 0 59 0 0 17 0 0 % L
% Met: 25 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 59 25 9 0 0 0 0 0 0 0 0 25 9 0 % N
% Pro: 0 0 59 9 0 25 0 0 0 0 0 0 9 9 9 % P
% Gln: 0 0 0 0 17 0 9 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 9 0 0 0 17 0 9 0 0 % R
% Ser: 9 0 9 0 17 0 0 50 25 9 0 0 34 0 0 % S
% Thr: 0 0 0 0 0 42 0 0 25 0 0 0 0 0 0 % T
% Val: 0 9 0 0 34 0 0 0 9 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 17 0 0 0 0 0 67 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _