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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPC5
All Species:
20
Human Site:
S249
Identified Species:
40
UniProt:
P78333
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78333
NP_004457.1
572
63707
S249
L
H
F
S
K
E
C
S
R
A
L
L
K
M
Q
Chimpanzee
Pan troglodytes
A5A6P7
580
65546
G253
L
K
F
S
K
D
C
G
R
M
L
T
R
M
W
Rhesus Macaque
Macaca mulatta
XP_001097558
580
65585
G253
L
K
F
S
K
D
C
G
R
M
L
T
R
M
W
Dog
Lupus familis
XP_542637
1141
126362
S785
L
H
F
S
K
E
C
S
K
A
L
L
R
M
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAL5
572
63773
S249
I
H
F
S
K
E
C
S
R
A
L
L
K
M
Q
Rat
Rattus norvegicus
P13265
597
67030
G252
L
K
F
S
K
D
C
G
R
M
L
T
R
M
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512016
621
68630
S331
L
Q
L
S
K
E
C
S
K
A
L
L
R
M
Q
Chicken
Gallus gallus
P50593
550
61065
T244
V
S
L
S
H
E
C
T
R
A
V
M
K
L
M
Frog
Xenopus laevis
NP_001084188
556
63021
V245
V
N
P
T
P
Q
C
V
K
A
M
L
K
M
T
Zebra Danio
Brachydanio rerio
XP_001920549
337
37530
Q80
H
T
L
S
I
L
H
Q
S
Q
R
D
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24114
626
69013
D300
L
Y
G
E
Q
L
T
D
T
C
K
L
H
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138966
605
67526
T248
M
P
L
T
R
R
C
T
R
A
L
M
Q
M
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
42.2
36.4
N.A.
85.6
41.2
N.A.
62.6
23.6
27.1
26.2
N.A.
26.6
N.A.
N.A.
27.6
Protein Similarity:
100
60.6
60.8
41.1
N.A.
92.8
60.2
N.A.
74.4
47.5
50.7
40.5
N.A.
44.2
N.A.
N.A.
46.7
P-Site Identity:
100
53.3
53.3
86.6
N.A.
93.3
53.3
N.A.
73.3
40
33.3
6.6
N.A.
13.3
N.A.
N.A.
33.3
P-Site Similarity:
100
66.6
66.6
100
N.A.
100
66.6
N.A.
86.6
73.3
73.3
6.6
N.A.
33.3
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
59
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
84
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
25
0
9
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
9
0
42
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
25
0
0
0
0
0
0
0
% G
% His:
9
25
0
0
9
0
9
0
0
0
0
0
9
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
25
0
0
59
0
0
0
25
0
9
0
34
0
0
% K
% Leu:
59
0
34
0
0
17
0
0
0
0
67
50
9
17
9
% L
% Met:
9
0
0
0
0
0
0
0
0
25
9
17
0
75
9
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
9
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
9
9
0
9
0
9
0
0
9
0
34
% Q
% Arg:
0
0
0
0
9
9
0
0
59
0
9
0
42
0
9
% R
% Ser:
0
9
0
75
0
0
0
34
9
0
0
0
0
9
9
% S
% Thr:
0
9
0
17
0
0
9
17
9
0
0
25
0
0
9
% T
% Val:
17
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _