KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPC5
All Species:
1.21
Human Site:
S376
Identified Species:
2.42
UniProt:
P78333
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78333
NP_004457.1
572
63707
S376
M
K
T
T
T
R
N
S
E
E
T
L
A
N
R
Chimpanzee
Pan troglodytes
A5A6P7
580
65546
H380
L
K
V
A
R
V
E
H
E
E
T
L
S
S
R
Rhesus Macaque
Macaca mulatta
XP_001097558
580
65585
H380
L
K
V
A
H
V
E
H
E
E
T
L
S
S
R
Dog
Lupus familis
XP_542637
1141
126362
D912
M
K
I
S
P
R
N
D
E
E
T
L
A
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAL5
572
63773
G376
M
K
I
S
A
R
N
G
E
E
T
L
A
N
R
Rat
Rattus norvegicus
P13265
597
67030
H379
L
K
V
A
R
V
E
H
E
E
T
L
S
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512016
621
68630
D458
M
K
I
S
S
A
R
D
N
E
E
T
L
S
N
Chicken
Gallus gallus
P50593
550
61065
A371
E
A
K
S
S
A
V
A
L
E
M
L
V
L
D
Frog
Xenopus laevis
NP_001084188
556
63021
V355
Q
G
R
Q
A
R
S
V
S
D
T
N
F
N
I
Zebra Danio
Brachydanio rerio
XP_001920549
337
37530
V174
H
A
S
L
P
A
R
V
F
L
Q
A
L
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24114
626
69013
S415
T
P
S
L
T
P
Y
S
S
G
E
P
D
A
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138966
605
67526
P374
N
I
P
I
A
P
N
P
A
I
P
L
D
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
42.2
36.4
N.A.
85.6
41.2
N.A.
62.6
23.6
27.1
26.2
N.A.
26.6
N.A.
N.A.
27.6
Protein Similarity:
100
60.6
60.8
41.1
N.A.
92.8
60.2
N.A.
74.4
47.5
50.7
40.5
N.A.
44.2
N.A.
N.A.
46.7
P-Site Identity:
100
40
40
66.6
N.A.
73.3
40
N.A.
20
13.3
20
0
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
60
60
73.3
N.A.
80
60
N.A.
40
33.3
33.3
13.3
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
25
25
25
0
9
9
0
0
9
25
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
17
0
9
0
0
17
0
9
% D
% Glu:
9
0
0
0
0
0
25
0
50
67
17
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% F
% Gly:
0
9
0
0
0
0
0
9
0
9
0
0
0
0
9
% G
% His:
9
0
0
0
9
0
0
25
0
0
0
0
0
9
0
% H
% Ile:
0
9
25
9
0
0
0
0
0
9
0
0
0
0
9
% I
% Lys:
0
59
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
0
0
17
0
0
0
0
9
9
0
67
17
9
17
% L
% Met:
34
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
34
0
9
0
0
9
0
34
9
% N
% Pro:
0
9
9
0
17
17
0
9
0
0
9
9
0
0
0
% P
% Gln:
9
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
9
0
17
34
17
0
0
0
0
0
0
0
50
% R
% Ser:
0
0
17
34
17
0
9
17
17
0
0
0
25
34
0
% S
% Thr:
9
0
9
9
17
0
0
0
0
0
59
9
0
0
0
% T
% Val:
0
0
25
0
0
25
9
17
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _