KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPC5
All Species:
12.12
Human Site:
S390
Identified Species:
24.24
UniProt:
P78333
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78333
NP_004457.1
572
63707
S390
R
R
K
E
F
I
N
S
L
R
L
Y
R
S
F
Chimpanzee
Pan troglodytes
A5A6P7
580
65546
K394
R
R
R
E
L
I
Q
K
L
K
S
F
I
S
F
Rhesus Macaque
Macaca mulatta
XP_001097558
580
65585
K394
R
R
R
E
L
I
Q
K
L
K
S
F
I
S
F
Dog
Lupus familis
XP_542637
1141
126362
S926
G
R
K
E
F
I
N
S
L
R
L
Y
R
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAL5
572
63773
S390
R
R
K
E
F
I
N
S
L
R
L
H
G
S
F
Rat
Rattus norvegicus
P13265
597
67030
K393
R
R
R
E
L
I
Q
K
L
K
S
F
I
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512016
621
68630
D472
N
R
R
K
E
F
I
D
S
L
R
L
Y
K
T
Chicken
Gallus gallus
P50593
550
61065
A385
D
A
K
G
N
L
T
A
L
K
S
Y
W
V
T
Frog
Xenopus laevis
NP_001084188
556
63021
P369
I
R
F
K
A
Y
G
P
E
E
R
P
T
T
A
Zebra Danio
Brachydanio rerio
XP_001920549
337
37530
T188
L
G
I
E
I
I
N
T
T
D
H
I
Q
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24114
626
69013
N429
R
P
P
P
H
K
N
N
V
K
W
A
T
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138966
605
67526
S388
L
L
L
Q
F
V
G
S
L
D
S
S
K
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
42.2
36.4
N.A.
85.6
41.2
N.A.
62.6
23.6
27.1
26.2
N.A.
26.6
N.A.
N.A.
27.6
Protein Similarity:
100
60.6
60.8
41.1
N.A.
92.8
60.2
N.A.
74.4
47.5
50.7
40.5
N.A.
44.2
N.A.
N.A.
46.7
P-Site Identity:
100
46.6
46.6
86.6
N.A.
86.6
46.6
N.A.
6.6
20
6.6
20
N.A.
13.3
N.A.
N.A.
26.6
P-Site Similarity:
100
66.6
66.6
93.3
N.A.
93.3
66.6
N.A.
20
40
20
33.3
N.A.
33.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
9
0
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
9
0
17
0
0
0
9
0
% D
% Glu:
0
0
0
59
9
0
0
0
9
9
0
0
0
0
0
% E
% Phe:
0
0
9
0
34
9
0
0
0
0
0
25
0
0
50
% F
% Gly:
9
9
0
9
0
0
17
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
9
9
0
0
0
% H
% Ile:
9
0
9
0
9
59
9
0
0
0
0
9
25
0
0
% I
% Lys:
0
0
34
17
0
9
0
25
0
42
0
0
9
9
0
% K
% Leu:
17
9
9
0
25
9
0
0
67
9
25
9
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
42
9
0
0
0
0
0
0
0
% N
% Pro:
0
9
9
9
0
0
0
9
0
0
0
9
0
0
9
% P
% Gln:
0
0
0
9
0
0
25
0
0
0
0
0
9
0
0
% Q
% Arg:
50
67
34
0
0
0
0
0
0
25
17
0
17
0
0
% R
% Ser:
0
0
0
0
0
0
0
34
9
0
42
9
0
50
9
% S
% Thr:
0
0
0
0
0
0
9
9
9
0
0
0
17
17
17
% T
% Val:
0
0
0
0
0
9
0
0
9
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
25
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _