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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPC5
All Species:
8.48
Human Site:
S541
Identified Species:
16.97
UniProt:
P78333
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78333
NP_004457.1
572
63707
S541
I
H
Q
T
D
T
G
S
T
L
D
T
T
G
A
Chimpanzee
Pan troglodytes
A5A6P7
580
65546
K545
S
N
Q
Q
A
T
P
K
D
N
E
I
S
T
F
Rhesus Macaque
Macaca mulatta
XP_001097558
580
65585
K545
N
N
Q
Q
A
T
P
K
D
N
E
I
S
T
F
Dog
Lupus familis
XP_542637
1141
126362
N1085
F
Q
G
L
C
E
Q
N
L
N
P
E
A
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAL5
572
63773
S541
V
H
R
A
D
H
G
S
T
L
D
T
T
S
T
Rat
Rattus norvegicus
P13265
597
67030
K544
N
K
Q
H
G
N
Q
K
D
N
E
I
T
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512016
621
68630
S592
D
G
C
G
G
S
G
S
G
E
V
R
K
I
K
Chicken
Gallus gallus
P50593
550
61065
G519
H
A
I
P
K
Q
S
G
H
G
V
I
G
A
S
Frog
Xenopus laevis
NP_001084188
556
63021
S491
I
D
I
A
V
D
E
S
S
G
E
G
S
G
S
Zebra Danio
Brachydanio rerio
XP_001920549
337
37530
V308
W
T
E
P
V
N
S
V
Q
H
S
T
G
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24114
626
69013
T588
I
E
E
S
E
G
T
T
T
N
E
V
E
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138966
605
67526
G544
S
F
E
P
T
S
R
G
A
G
E
T
R
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
42.2
36.4
N.A.
85.6
41.2
N.A.
62.6
23.6
27.1
26.2
N.A.
26.6
N.A.
N.A.
27.6
Protein Similarity:
100
60.6
60.8
41.1
N.A.
92.8
60.2
N.A.
74.4
47.5
50.7
40.5
N.A.
44.2
N.A.
N.A.
46.7
P-Site Identity:
100
13.3
13.3
0
N.A.
60
13.3
N.A.
13.3
0
20
13.3
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
33.3
6.6
N.A.
73.3
26.6
N.A.
20
6.6
46.6
20
N.A.
46.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
17
0
0
0
9
0
0
0
9
9
17
% A
% Cys:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
17
9
0
0
25
0
17
0
0
0
0
% D
% Glu:
0
9
25
0
9
9
9
0
0
9
50
9
9
0
0
% E
% Phe:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
17
% F
% Gly:
0
9
9
9
17
9
25
17
9
25
0
9
17
17
0
% G
% His:
9
17
0
9
0
9
0
0
9
9
0
0
0
0
0
% H
% Ile:
25
0
17
0
0
0
0
0
0
0
0
34
0
9
0
% I
% Lys:
0
9
0
0
9
0
0
25
0
0
0
0
9
0
17
% K
% Leu:
0
0
0
9
0
0
0
0
9
17
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
17
17
0
0
0
17
0
9
0
42
0
0
0
9
0
% N
% Pro:
0
0
0
25
0
0
17
0
0
0
9
0
0
0
9
% P
% Gln:
0
9
34
17
0
9
17
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
9
0
0
0
0
9
9
9
9
% R
% Ser:
17
0
0
9
0
17
17
34
9
0
9
0
25
17
25
% S
% Thr:
0
9
0
9
9
25
9
9
25
0
0
34
25
34
9
% T
% Val:
9
0
0
0
17
0
0
9
0
0
17
9
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _