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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPC5
All Species:
4.55
Human Site:
T515
Identified Species:
9.09
UniProt:
P78333
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78333
NP_004457.1
572
63707
T515
G
S
G
E
V
K
R
T
L
K
I
T
D
W
M
Chimpanzee
Pan troglodytes
A5A6P7
580
65546
Q519
G
M
M
K
V
K
N
Q
L
R
F
L
A
E
L
Rhesus Macaque
Macaca mulatta
XP_001097558
580
65585
Q519
G
M
M
K
V
K
N
Q
L
R
F
L
A
E
L
Dog
Lupus familis
XP_542637
1141
126362
K1059
L
S
E
E
V
L
G
K
V
L
S
A
V
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAL5
572
63773
T515
G
S
G
E
V
K
R
T
L
K
I
T
N
W
M
Rat
Rattus norvegicus
P13265
597
67030
Q518
G
M
M
K
V
K
N
Q
L
R
F
L
A
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512016
621
68630
Q566
H
E
R
W
D
L
F
Q
M
G
S
G
G
S
I
Chicken
Gallus gallus
P50593
550
61065
D493
G
S
G
D
S
C
P
D
D
V
C
V
K
R
L
Frog
Xenopus laevis
NP_001084188
556
63021
L465
I
R
Q
Q
I
M
A
L
R
I
M
T
N
K
M
Zebra Danio
Brachydanio rerio
XP_001920549
337
37530
R282
D
A
V
A
H
A
Q
R
S
T
A
R
I
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24114
626
69013
E562
Q
I
G
D
D
E
E
E
Y
G
G
A
H
G
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138966
605
67526
N518
G
S
G
D
G
V
E
N
A
T
L
P
Q
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
42.2
36.4
N.A.
85.6
41.2
N.A.
62.6
23.6
27.1
26.2
N.A.
26.6
N.A.
N.A.
27.6
Protein Similarity:
100
60.6
60.8
41.1
N.A.
92.8
60.2
N.A.
74.4
47.5
50.7
40.5
N.A.
44.2
N.A.
N.A.
46.7
P-Site Identity:
100
26.6
26.6
20
N.A.
93.3
26.6
N.A.
0
20
13.3
0
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
46.6
46.6
26.6
N.A.
100
46.6
N.A.
13.3
33.3
40
13.3
N.A.
20
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
9
9
0
9
0
9
17
25
0
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
0
0
25
17
0
0
9
9
0
0
0
9
0
0
% D
% Glu:
0
9
9
25
0
9
17
9
0
0
0
0
0
25
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
25
0
0
9
0
% F
% Gly:
59
0
42
0
9
0
9
0
0
17
9
9
9
17
0
% G
% His:
9
0
0
0
9
0
0
0
0
0
0
0
9
9
0
% H
% Ile:
9
9
0
0
9
0
0
0
0
9
17
0
9
0
9
% I
% Lys:
0
0
0
25
0
42
0
9
0
17
0
0
9
9
0
% K
% Leu:
9
0
0
0
0
17
0
9
42
9
9
25
0
0
34
% L
% Met:
0
25
25
0
0
9
0
0
9
0
9
0
0
0
25
% M
% Asn:
0
0
0
0
0
0
25
9
0
0
0
0
17
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% P
% Gln:
9
0
9
9
0
0
9
34
0
0
0
0
9
0
0
% Q
% Arg:
0
9
9
0
0
0
17
9
9
25
0
9
0
9
0
% R
% Ser:
0
42
0
0
9
0
0
0
9
0
17
0
0
9
25
% S
% Thr:
0
0
0
0
0
0
0
17
0
17
0
25
0
0
0
% T
% Val:
0
0
9
0
50
9
0
0
9
9
0
9
9
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
17
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _