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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPC5
All Species:
34.85
Human Site:
Y257
Identified Species:
69.7
UniProt:
P78333
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78333
NP_004457.1
572
63707
Y257
R
A
L
L
K
M
Q
Y
C
P
H
C
Q
G
L
Chimpanzee
Pan troglodytes
A5A6P7
580
65546
Y261
R
M
L
T
R
M
W
Y
C
S
Y
C
Q
G
L
Rhesus Macaque
Macaca mulatta
XP_001097558
580
65585
Y261
R
M
L
T
R
M
W
Y
C
S
Y
C
Q
G
L
Dog
Lupus familis
XP_542637
1141
126362
Y793
K
A
L
L
R
M
Q
Y
C
P
H
C
Q
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAL5
572
63773
Y257
R
A
L
L
K
M
Q
Y
C
P
H
C
Q
S
L
Rat
Rattus norvegicus
P13265
597
67030
Y260
R
M
L
T
R
M
W
Y
C
S
Y
C
Q
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512016
621
68630
Y339
K
A
L
L
R
M
Q
Y
C
P
H
C
Q
A
L
Chicken
Gallus gallus
P50593
550
61065
Y252
R
A
V
M
K
L
M
Y
C
P
H
C
R
G
M
Frog
Xenopus laevis
NP_001084188
556
63021
Y253
K
A
M
L
K
M
T
Y
C
P
Y
C
S
G
L
Zebra Danio
Brachydanio rerio
XP_001920549
337
37530
P88
S
Q
R
D
L
S
S
P
A
A
S
A
P
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24114
626
69013
K308
T
C
K
L
H
L
L
K
M
H
Y
C
P
N
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138966
605
67526
Y256
R
A
L
M
Q
M
R
Y
C
G
Q
C
Q
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42
42.2
36.4
N.A.
85.6
41.2
N.A.
62.6
23.6
27.1
26.2
N.A.
26.6
N.A.
N.A.
27.6
Protein Similarity:
100
60.6
60.8
41.1
N.A.
92.8
60.2
N.A.
74.4
47.5
50.7
40.5
N.A.
44.2
N.A.
N.A.
46.7
P-Site Identity:
100
60
60
86.6
N.A.
93.3
60
N.A.
80
60
66.6
0
N.A.
13.3
N.A.
N.A.
60
P-Site Similarity:
100
73.3
73.3
100
N.A.
93.3
73.3
N.A.
93.3
93.3
86.6
0
N.A.
26.6
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
0
0
0
0
0
0
9
9
0
9
0
9
0
% A
% Cys:
0
9
0
0
0
0
0
0
84
0
0
92
0
0
9
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
0
0
59
9
% G
% His:
0
0
0
0
9
0
0
0
0
9
42
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
25
0
9
0
34
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
67
50
9
17
9
0
0
0
0
0
0
0
75
% L
% Met:
0
25
9
17
0
75
9
0
9
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
50
0
0
17
0
0
% P
% Gln:
0
9
0
0
9
0
34
0
0
0
9
0
67
0
0
% Q
% Arg:
59
0
9
0
42
0
9
0
0
0
0
0
9
0
0
% R
% Ser:
9
0
0
0
0
9
9
0
0
25
9
0
9
17
0
% S
% Thr:
9
0
0
25
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
42
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _