KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GABRE
All Species:
10.3
Human Site:
S424
Identified Species:
25.19
UniProt:
P78334
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78334
NP_004952.2
506
57972
S424
G
E
E
R
P
S
C
S
A
Q
Q
P
P
S
P
Chimpanzee
Pan troglodytes
XP_521310
533
60822
S451
G
E
E
R
P
S
C
S
A
Q
Q
P
P
S
P
Rhesus Macaque
Macaca mulatta
XP_001093865
506
57830
S424
G
E
D
R
P
S
C
S
A
Q
Q
P
P
S
P
Dog
Lupus familis
XP_549340
506
58070
S424
Q
I
E
D
S
E
E
S
D
E
E
E
G
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P27681
467
54285
P386
L
D
M
R
P
P
P
P
V
M
I
T
L
N
N
Rat
Rattus norvegicus
Q9ES14
506
59200
E424
V
T
Y
E
E
N
A
E
E
G
Y
Q
W
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514189
455
53087
N374
S
F
T
A
I
T
I
N
N
V
I
H
W
P
P
Chicken
Gallus gallus
P34904
457
53165
N375
S
F
T
A
I
N
I
N
I
N
N
I
M
H
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920261
449
51874
P368
V
L
D
V
G
P
P
P
T
V
I
T
L
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O18276
550
62439
A466
L
K
G
A
R
P
H
A
S
L
N
H
K
T
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.4
97.6
76.4
N.A.
43
70.9
N.A.
47.2
46.8
N.A.
43.4
N.A.
N.A.
N.A.
30.7
N.A.
Protein Similarity:
100
81.2
98.6
84.7
N.A.
61.8
82.4
N.A.
65
65
N.A.
61.2
N.A.
N.A.
N.A.
49.2
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
13.3
13.3
N.A.
6.6
0
N.A.
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
20
N.A.
20
13.3
N.A.
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
30
0
0
10
10
30
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
20
10
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
30
30
10
10
10
10
10
10
10
10
10
0
0
0
% E
% Phe:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
30
0
10
0
10
0
0
0
0
10
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
20
0
10
10
% H
% Ile:
0
10
0
0
20
0
20
0
10
0
30
10
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
20
10
0
0
0
0
0
0
0
10
0
0
20
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
20
0
20
10
10
20
0
0
20
20
% N
% Pro:
0
0
0
0
40
30
20
20
0
0
0
30
30
20
50
% P
% Gln:
10
0
0
0
0
0
0
0
0
30
30
10
0
0
0
% Q
% Arg:
0
0
0
40
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
0
0
0
10
30
0
40
10
0
0
0
0
40
10
% S
% Thr:
0
10
20
0
0
10
0
0
10
0
0
20
0
10
0
% T
% Val:
20
0
0
10
0
0
0
0
10
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
10
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _