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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPP38
All Species:
13.33
Human Site:
S235
Identified Species:
32.59
UniProt:
P78345
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78345
NP_001091059.1
283
31834
S235
D
R
E
L
L
D
T
S
F
E
D
L
S
K
P
Chimpanzee
Pan troglodytes
XP_521418
283
31664
S235
D
R
E
L
L
D
T
S
F
E
D
L
S
K
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q80UU2
280
31111
S230
D
N
E
I
L
D
T
S
F
D
D
L
T
K
L
Rat
Rattus norvegicus
NP_001028235
272
30069
S224
D
K
E
V
L
D
T
S
F
D
D
L
T
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418633
293
32357
A242
E
Q
L
A
E
T
P
A
E
E
L
S
S
Q
K
Frog
Xenopus laevis
NP_001087856
279
30874
S233
A
S
S
E
P
L
G
S
R
K
R
K
H
M
K
Zebra Danio
Brachydanio rerio
NP_001002525
265
29470
K225
T
E
I
G
Q
K
R
K
L
E
E
L
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002320256
183
20339
G143
R
G
G
S
L
R
L
G
E
L
V
K
L
K
T
Maize
Zea mays
NP_001152178
186
20193
R146
D
N
K
G
G
S
V
R
L
G
H
V
V
N
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192088
167
18841
N127
P
V
L
Y
V
R
D
N
K
R
A
S
L
R
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
N.A.
N.A.
N.A.
75.9
73.1
N.A.
N.A.
50.1
48.7
43.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
N.A.
N.A.
N.A.
84.4
83
N.A.
N.A.
65.8
64.6
59.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
N.A.
N.A.
66.6
60
N.A.
N.A.
13.3
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
86.6
93.3
N.A.
N.A.
40
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
24
21.5
N.A.
21.5
N.A.
N.A.
Protein Similarity:
38.8
37.4
N.A.
36.7
N.A.
N.A.
P-Site Identity:
13.3
6.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
20
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
40
10
0
0
20
40
0
0
0
10
% D
% Glu:
10
10
40
10
10
0
0
0
20
40
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% F
% Gly:
0
10
10
20
10
0
10
10
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
0
0
10
0
10
10
10
0
20
0
40
20
% K
% Leu:
0
0
20
20
50
10
10
0
20
10
10
50
20
0
30
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
20
0
0
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
10
0
0
0
10
0
10
0
0
0
0
0
0
0
20
% P
% Gln:
0
10
0
0
10
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
20
0
0
0
20
10
10
10
10
10
0
0
20
0
% R
% Ser:
0
10
10
10
0
10
0
50
0
0
0
20
40
10
0
% S
% Thr:
10
0
0
0
0
10
40
0
0
0
0
0
20
0
10
% T
% Val:
0
10
0
10
10
0
10
0
0
0
10
10
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _