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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPP38
All Species:
4.55
Human Site:
S253
Identified Species:
11.11
UniProt:
P78345
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78345
NP_001091059.1
283
31834
S253
L
A
D
G
R
Q
A
S
V
T
L
Q
P
L
K
Chimpanzee
Pan troglodytes
XP_521418
283
31664
S253
L
A
D
G
R
Q
A
S
V
T
L
Q
P
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q80UU2
280
31111
A248
K
L
A
E
G
G
Q
A
S
A
A
T
L
Q
P
Rat
Rattus norvegicus
NP_001028235
272
30069
P242
L
A
E
G
G
Q
A
P
A
A
T
L
Q
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418633
293
32357
L260
T
E
S
N
Q
L
D
L
S
R
V
I
L
Q
P
Frog
Xenopus laevis
NP_001087856
279
30874
I251
E
T
T
D
V
S
D
I
K
L
Q
A
L
K
V
Zebra Danio
Brachydanio rerio
NP_001002525
265
29470
V243
L
A
L
Q
P
L
K
V
K
K
T
I
P
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002320256
183
20339
N161
I
G
V
K
A
R
G
N
A
I
N
E
I
V
G
Maize
Zea mays
NP_001152178
186
20193
K164
L
A
I
G
V
K
A
K
D
S
V
L
N
K
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192088
167
18841
A145
V
K
L
K
T
A
L
A
I
G
I
K
A
R
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
N.A.
N.A.
N.A.
75.9
73.1
N.A.
N.A.
50.1
48.7
43.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
N.A.
N.A.
N.A.
84.4
83
N.A.
N.A.
65.8
64.6
59.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
N.A.
N.A.
0
33.3
N.A.
N.A.
0
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
6.6
40
N.A.
N.A.
13.3
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
24
21.5
N.A.
21.5
N.A.
N.A.
Protein Similarity:
38.8
37.4
N.A.
36.7
N.A.
N.A.
P-Site Identity:
0
26.6
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
46.6
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
10
0
10
10
40
20
20
20
10
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
10
0
0
20
0
10
0
0
0
0
0
0
% D
% Glu:
10
10
10
10
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
40
20
10
10
0
0
10
0
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
10
10
10
10
20
10
0
0
% I
% Lys:
10
10
0
20
0
10
10
10
20
10
0
10
0
20
20
% K
% Leu:
50
10
20
0
0
20
10
10
0
10
20
20
30
20
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
0
10
0
10
10
0
% N
% Pro:
0
0
0
0
10
0
0
10
0
0
0
0
30
10
30
% P
% Gln:
0
0
0
10
10
30
10
0
0
0
10
20
10
20
0
% Q
% Arg:
0
0
0
0
20
10
0
0
0
10
0
0
0
10
0
% R
% Ser:
0
0
10
0
0
10
0
20
20
10
0
0
0
0
0
% S
% Thr:
10
10
10
0
10
0
0
0
0
20
20
10
0
0
10
% T
% Val:
10
0
10
0
20
0
0
10
20
0
20
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _