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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPP38 All Species: 6.06
Human Site: S87 Identified Species: 14.81
UniProt: P78345 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78345 NP_001091059.1 283 31834 S87 C S I A V D I S E N L K E K K
Chimpanzee Pan troglodytes XP_521418 283 31664 S87 C S I A V D I S E N L K E K K
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q80UU2 280 31111 E82 Q S C R P D I E I S E D P K E
Rat Rattus norvegicus NP_001028235 272 30069 G76 K Q R G G L V G T S E E P Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418633 293 32357 S94 S K C D G S N S E L P A E E E
Frog Xenopus laevis NP_001087856 279 30874 C85 A E T Q K E S C E A T A S K E
Zebra Danio Brachydanio rerio NP_001002525 265 29470 Q84 A S K P T E E Q N P A S E P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002320256 183 20339
Maize Zea mays NP_001152178 186 20193
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_192088 167 18841
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 N.A. N.A. N.A. 75.9 73.1 N.A. N.A. 50.1 48.7 43.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 N.A. N.A. N.A. 84.4 83 N.A. N.A. 65.8 64.6 59.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. N.A. N.A. 26.6 0 N.A. N.A. 20 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. N.A. N.A. 40 33.3 N.A. N.A. 33.3 26.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 24 21.5 N.A. 21.5 N.A. N.A.
Protein Similarity: 38.8 37.4 N.A. 36.7 N.A. N.A.
P-Site Identity: 0 0 N.A. 0 N.A. N.A.
P-Site Similarity: 0 0 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 20 0 0 0 0 0 10 10 20 0 0 10 % A
% Cys: 20 0 20 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 30 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 10 0 0 0 20 10 10 40 0 20 10 40 10 40 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 20 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 20 0 0 0 30 0 10 0 0 0 0 0 0 % I
% Lys: 10 10 10 0 10 0 0 0 0 0 0 20 0 40 20 % K
% Leu: 0 0 0 0 0 10 0 0 0 10 20 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 10 20 0 0 0 0 0 % N
% Pro: 0 0 0 10 10 0 0 0 0 10 10 0 20 10 0 % P
% Gln: 10 10 0 10 0 0 0 10 0 0 0 0 0 10 0 % Q
% Arg: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 40 0 0 0 10 10 30 0 20 0 10 10 0 0 % S
% Thr: 0 0 10 0 10 0 0 0 10 0 10 0 0 0 0 % T
% Val: 0 0 0 0 20 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _