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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPP30
All Species:
23.33
Human Site:
S251
Identified Species:
42.78
UniProt:
P78346
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78346
NP_001098016.1
268
29321
S251
T
V
K
K
P
R
P
S
E
G
D
E
D
C
L
Chimpanzee
Pan troglodytes
XP_521557
322
35546
S251
T
V
K
K
P
R
P
S
E
G
D
E
D
C
L
Rhesus Macaque
Macaca mulatta
XP_001087609
268
29360
S251
T
V
K
K
P
R
P
S
E
G
D
E
D
C
L
Dog
Lupus familis
XP_534959
268
29379
S251
T
V
K
K
P
R
P
S
E
A
D
E
D
S
L
Cat
Felis silvestris
Mouse
Mus musculus
O88796
268
29455
S251
T
V
K
K
P
R
P
S
E
A
D
D
E
S
L
Rat
Rattus norvegicus
XP_001063377
268
29467
S251
T
V
K
K
P
R
S
S
E
A
E
D
E
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514397
324
35863
S308
T
V
R
K
P
Q
T
S
E
D
V
D
A
G
P
Chicken
Gallus gallus
XP_421667
267
29398
V251
T
V
K
K
L
H
K
V
E
E
E
E
T
V
P
Frog
Xenopus laevis
NP_001088047
265
29254
C249
V
Y
T
V
K
K
T
C
L
E
E
E
E
A
E
Zebra Danio
Brachydanio rerio
NP_001013497
265
29368
L247
T
M
K
K
P
Q
I
L
Q
K
E
E
E
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784366
221
24699
N205
A
K
A
A
I
S
T
N
C
Q
S
A
L
V
H
Poplar Tree
Populus trichocarpa
XP_002314208
324
35807
D263
R
I
E
P
I
S
S
D
E
I
S
D
T
K
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38786
293
32206
N255
V
T
G
G
G
S
G
N
G
D
D
V
V
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.9
98.5
94
N.A.
90.3
90.6
N.A.
65.7
73.5
69
60.8
N.A.
N.A.
N.A.
N.A.
36.5
Protein Similarity:
100
82.9
99.6
97.7
N.A.
95.9
95.9
N.A.
75.3
88.8
82.4
77.6
N.A.
N.A.
N.A.
N.A.
50.3
P-Site Identity:
100
100
100
86.6
N.A.
73.3
60
N.A.
40
40
6.6
33.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
80
N.A.
60
46.6
26.6
66.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
33.9
N.A.
N.A.
N.A.
25.6
N.A.
Protein Similarity:
46.6
N.A.
N.A.
N.A.
47.7
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
0
0
0
24
0
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
24
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
16
47
31
31
0
8
% D
% Glu:
0
0
8
0
0
0
0
0
70
16
31
54
31
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
8
0
8
24
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
16
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
62
70
8
8
8
0
0
8
0
0
0
8
0
% K
% Leu:
0
0
0
0
8
0
0
8
8
0
0
0
8
0
47
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
16
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
8
62
0
39
0
0
0
0
0
0
0
16
% P
% Gln:
0
0
0
0
0
16
0
0
8
8
0
0
0
0
0
% Q
% Arg:
8
0
8
0
0
47
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
24
16
54
0
0
16
0
0
24
0
% S
% Thr:
70
8
8
0
0
0
24
0
0
0
0
0
16
0
8
% T
% Val:
16
62
0
8
0
0
0
8
0
0
8
8
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _