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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2I
All Species:
26.97
Human Site:
S146
Identified Species:
84.76
UniProt:
P78347
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78347
NP_001509.3
998
112416
S146
E
K
M
L
R
D
Q
S
A
V
V
V
Q
G
L
Chimpanzee
Pan troglodytes
XP_001151627
998
112611
S146
E
K
M
L
R
D
Q
S
A
V
V
V
Q
G
L
Rhesus Macaque
Macaca mulatta
XP_001083724
957
108008
S146
E
K
M
L
R
D
Q
S
A
V
V
V
Q
G
L
Dog
Lupus familis
XP_848656
999
112438
S146
E
K
M
L
R
D
Q
S
A
V
V
V
Q
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESZ8
998
112247
S146
E
K
M
L
R
D
Q
S
A
V
V
V
Q
G
L
Rat
Rattus norvegicus
Q5U2Y1
979
110196
S146
E
K
M
L
R
D
Q
S
A
V
A
V
Q
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510406
994
111440
S146
E
K
I
L
R
D
Q
S
A
V
V
V
Q
G
L
Chicken
Gallus gallus
Frog
Xenopus laevis
B7ZQJ9
993
110556
G160
V
K
V
M
K
E
P
G
S
V
V
V
L
G
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.5
98.3
N.A.
97
95.3
N.A.
84.4
N.A.
25
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
95.6
99.1
N.A.
98.4
96.5
N.A.
90.2
N.A.
43.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
88
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
88
0
0
0
0
0
0
0
0
0
% D
% Glu:
88
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
13
0
0
0
0
0
100
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
100
0
0
13
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
88
0
0
0
0
0
0
0
0
13
0
100
% L
% Met:
0
0
75
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
88
0
0
0
0
0
88
0
0
% Q
% Arg:
0
0
0
0
88
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
88
13
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
13
0
13
0
0
0
0
0
0
100
88
100
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _