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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2I All Species: 14.55
Human Site: S301 Identified Species: 45.71
UniProt: P78347 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78347 NP_001509.3 998 112416 S301 D S T Q H V P S E T S E D P E
Chimpanzee Pan troglodytes XP_001151627 998 112611 S301 D S T Q H V P S E T S E D P E
Rhesus Macaque Macaca mulatta XP_001083724 957 108008 G301 V P E P A N A G K R K V R E F
Dog Lupus familis XP_848656 999 112438 S301 D S T Q H V P S E T S E D P E
Cat Felis silvestris
Mouse Mus musculus Q9ESZ8 998 112247 S300 D S T Q H V P S E T S E D P E
Rat Rattus norvegicus Q5U2Y1 979 110196 P301 E D D D Y S P P T K R P K S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510406 994 111440 D295 V E V T I E D D E Y S P P S K
Chicken Gallus gallus
Frog Xenopus laevis B7ZQJ9 993 110556 S313 L R Q N V L A S K H L L F S I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95.5 98.3 N.A. 97 95.3 N.A. 84.4 N.A. 25 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 95.6 99.1 N.A. 98.4 96.5 N.A. 90.2 N.A. 43.7 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 100 6.6 N.A. 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 100 N.A. 100 20 N.A. 20 N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 13 0 25 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 13 13 13 0 0 13 13 0 0 0 0 50 0 0 % D
% Glu: 13 13 13 0 0 13 0 0 63 0 0 50 0 13 50 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 13 % F
% Gly: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 50 0 0 0 0 13 0 0 0 0 0 % H
% Ile: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 13 % I
% Lys: 0 0 0 0 0 0 0 0 25 13 13 0 13 0 13 % K
% Leu: 13 0 0 0 0 13 0 0 0 0 13 13 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 13 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 13 0 13 0 0 63 13 0 0 0 25 13 50 0 % P
% Gln: 0 0 13 50 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 13 0 0 0 0 0 0 0 13 13 0 13 0 0 % R
% Ser: 0 50 0 0 0 13 0 63 0 0 63 0 0 38 13 % S
% Thr: 0 0 50 13 0 0 0 0 13 50 0 0 0 0 0 % T
% Val: 25 0 13 0 13 50 0 0 0 0 0 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 13 0 0 0 0 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _