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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLG4
All Species:
21.82
Human Site:
S422
Identified Species:
60
UniProt:
P78352
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78352
NP_001356.1
724
80495
S422
S
L
G
S
G
T
A
S
L
R
S
N
P
K
R
Chimpanzee
Pan troglodytes
XP_523833
721
80070
S419
S
L
G
S
G
T
A
S
L
R
S
N
P
K
R
Rhesus Macaque
Macaca mulatta
XP_001098707
880
97846
S575
S
I
S
S
G
S
G
S
L
R
T
S
Q
K
R
Dog
Lupus familis
XP_546580
760
84228
S464
S
L
G
S
G
T
A
S
L
R
S
N
P
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q62108
724
80454
S422
S
L
G
S
G
T
A
S
L
R
S
N
P
K
R
Rat
Rattus norvegicus
P31016
724
80447
S422
S
L
G
S
G
T
A
S
L
R
S
N
P
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ00
468
52501
C181
K
K
D
N
L
I
P
C
K
E
A
G
L
K
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6R005
801
89122
A501
S
S
L
V
S
A
A
A
S
L
R
S
G
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P31007
970
106654
V668
E
W
W
Q
A
R
R
V
L
G
D
N
E
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
62.5
89.6
N.A.
99.5
99.8
N.A.
N.A.
21.8
N.A.
71.2
N.A.
44.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
72.7
91.5
N.A.
99.8
99.8
N.A.
N.A.
38.2
N.A.
79.4
N.A.
58
N.A.
N.A.
N.A.
P-Site Identity:
100
100
53.3
100
N.A.
100
100
N.A.
N.A.
6.6
N.A.
26.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
100
N.A.
100
100
N.A.
N.A.
20
N.A.
40
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
67
12
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
12
0
0
12
0
% D
% Glu:
12
0
0
0
0
0
0
0
0
12
0
0
12
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
56
0
67
0
12
0
0
12
0
12
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
12
0
0
0
0
0
0
12
0
0
0
0
89
0
% K
% Leu:
0
56
12
0
12
0
0
0
78
12
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
0
67
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
0
56
0
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
12
12
0
0
67
12
0
0
0
78
% R
% Ser:
78
12
12
67
12
12
0
67
12
0
56
23
0
0
0
% S
% Thr:
0
0
0
0
0
56
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _