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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIP4K2B
All Species:
29.39
Human Site:
T23
Identified Species:
58.79
UniProt:
P78356
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78356
NP_003550.1
416
47378
T23
L
S
A
S
K
T
K
T
K
K
K
H
F
V
C
Chimpanzee
Pan troglodytes
XP_001172818
377
42820
T23
L
S
A
S
K
T
K
T
K
K
K
H
F
V
C
Rhesus Macaque
Macaca mulatta
XP_001099389
382
43672
E24
P
S
I
R
Q
T
Q
E
I
N
E
L
S
H
V
Dog
Lupus familis
XP_548154
416
47327
T23
L
S
A
S
K
T
K
T
K
K
K
H
F
V
C
Cat
Felis silvestris
Mouse
Mus musculus
Q80XI4
416
47300
T23
L
S
A
S
K
T
K
T
K
K
K
H
F
V
C
Rat
Rattus norvegicus
O88377
416
47245
T23
L
S
A
S
K
T
K
T
K
K
K
H
F
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510625
479
54696
T25
N
T
P
K
P
A
D
T
P
K
G
H
T
L
V
Chicken
Gallus gallus
Q5F356
405
46073
V23
K
T
K
K
K
H
F
V
V
Q
K
V
K
L
F
Frog
Xenopus laevis
Q5PQ01
419
47633
T31
A
T
T
A
K
T
K
T
K
K
K
H
F
V
Q
Zebra Danio
Brachydanio rerio
Q6IQE1
416
47361
T23
M
L
A
P
K
T
K
T
K
K
R
H
F
M
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392797
416
47916
H23
K
K
H
F
R
V
K
H
Q
K
V
K
L
F
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY89
769
87385
T252
T
T
S
G
L
T
R
T
S
E
R
Y
P
D
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
69.4
99.2
N.A.
99
98.3
N.A.
62
77.6
67.7
65.3
N.A.
N.A.
58.6
N.A.
N.A.
Protein Similarity:
100
89.4
80
99.7
N.A.
99.7
99
N.A.
73
88.9
82
80.5
N.A.
N.A.
74
N.A.
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
20
13.3
66.6
60
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
33.3
33.3
80
80
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
50
9
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
9
% D
% Glu:
0
0
0
0
0
0
0
9
0
9
9
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
9
0
0
0
0
0
59
9
9
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
9
0
0
9
0
9
0
0
0
67
0
9
0
% H
% Ile:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
17
9
9
17
67
0
67
0
59
75
59
9
9
0
0
% K
% Leu:
42
9
0
0
9
0
0
0
0
0
0
9
9
17
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
9
0
9
9
9
0
0
0
9
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
9
0
9
0
9
9
0
0
0
0
17
% Q
% Arg:
0
0
0
9
9
0
9
0
0
0
17
0
0
0
9
% R
% Ser:
0
50
9
42
0
0
0
0
9
0
0
0
9
0
0
% S
% Thr:
9
34
9
0
0
75
0
75
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
9
0
9
9
0
9
9
0
50
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _