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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIP4K2B
All Species:
30.61
Human Site:
Y143
Identified Species:
61.21
UniProt:
P78356
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78356
NP_003550.1
416
47378
Y143
G
T
R
F
L
T
T
Y
D
R
R
F
V
I
K
Chimpanzee
Pan troglodytes
XP_001172818
377
42820
F139
Q
G
R
C
G
T
R
F
L
T
T
Y
D
R
R
Rhesus Macaque
Macaca mulatta
XP_001099389
382
43672
Y141
I
L
K
K
Y
H
Q
Y
I
V
E
C
H
G
I
Dog
Lupus familis
XP_548154
416
47327
Y143
G
T
R
F
L
T
T
Y
D
R
R
F
V
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80XI4
416
47300
Y143
G
T
R
F
L
T
T
Y
D
R
R
F
V
I
K
Rat
Rattus norvegicus
O88377
416
47245
Y143
G
T
R
F
L
T
T
Y
D
R
R
F
V
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510625
479
54696
Y207
G
A
R
F
H
I
S
Y
D
K
R
Y
I
I
K
Chicken
Gallus gallus
Q5F356
405
46073
Y137
G
A
R
F
H
T
S
Y
D
K
R
Y
I
I
K
Frog
Xenopus laevis
Q5PQ01
419
47633
Y149
D
G
R
F
L
L
S
Y
D
K
T
L
V
I
K
Zebra Danio
Brachydanio rerio
Q6IQE1
416
47361
Y141
E
G
L
L
F
T
S
Y
D
R
T
L
I
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392797
416
47916
Y136
G
A
K
F
Y
Q
S
Y
D
K
L
F
I
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY89
769
87385
H453
G
S
I
F
Y
L
S
H
D
D
R
F
V
I
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
69.4
99.2
N.A.
99
98.3
N.A.
62
77.6
67.7
65.3
N.A.
N.A.
58.6
N.A.
N.A.
Protein Similarity:
100
89.4
80
99.7
N.A.
99.7
99
N.A.
73
88.9
82
80.5
N.A.
N.A.
74
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
100
N.A.
100
100
N.A.
53.3
60
53.3
33.3
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
100
33.3
13.3
100
N.A.
100
100
N.A.
80
86.6
66.6
53.3
N.A.
N.A.
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
84
9
0
0
9
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
75
9
0
0
9
0
0
0
50
0
0
0
% F
% Gly:
67
25
0
0
9
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
17
9
0
9
0
0
0
0
9
0
0
% H
% Ile:
9
0
9
0
0
9
0
0
9
0
0
0
34
75
9
% I
% Lys:
0
0
17
9
0
0
0
0
0
34
0
0
0
0
84
% K
% Leu:
0
9
9
9
42
17
0
0
9
0
9
17
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
67
0
0
0
9
0
0
42
59
0
0
9
9
% R
% Ser:
0
9
0
0
0
0
50
0
0
0
0
0
0
0
0
% S
% Thr:
0
34
0
0
0
59
34
0
0
9
25
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
50
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
25
0
0
84
0
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _