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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK2
All Species:
22.12
Human Site:
T376
Identified Species:
60.83
UniProt:
P78362
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78362
NP_872633.1
688
77543
T376
E
L
A
N
I
D
P
T
W
I
E
S
P
K
T
Chimpanzee
Pan troglodytes
XP_001160812
687
77411
T375
E
L
A
N
I
D
P
T
W
I
E
S
P
K
T
Rhesus Macaque
Macaca mulatta
XP_001088614
687
77455
T375
E
L
A
N
I
D
P
T
W
I
E
S
P
K
T
Dog
Lupus familis
XP_849273
686
77402
A374
E
L
T
N
A
D
P
A
W
I
E
S
P
K
T
Cat
Felis silvestris
Mouse
Mus musculus
O54781
681
76738
T374
E
L
A
N
L
D
P
T
W
V
E
S
P
K
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508534
693
78060
T380
E
L
A
V
T
D
P
T
W
L
E
S
P
K
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001165329
695
78154
T383
E
L
V
D
T
D
Q
T
W
I
E
S
P
K
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
K468
E
A
A
L
D
E
I
K
L
L
L
S
V
R
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
S419
H
N
S
F
S
S
V
S
G
N
R
N
I
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
95.6
N.A.
93.9
N.A.
N.A.
87.8
N.A.
80.7
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
99.4
99.2
96.5
N.A.
95.4
N.A.
N.A.
91.9
N.A.
87.4
N.A.
N.A.
N.A.
N.A.
36
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
N.A.
N.A.
80
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
80
N.A.
93.3
N.A.
N.A.
86.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
67
0
12
0
0
12
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
12
78
0
0
0
0
0
0
0
0
0
% D
% Glu:
89
0
0
0
0
12
0
0
0
0
78
0
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
34
0
12
0
0
56
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
0
0
78
0
% K
% Leu:
0
78
0
12
12
0
0
0
12
23
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
56
0
0
0
0
0
12
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
67
0
0
0
0
0
78
12
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% R
% Ser:
0
0
12
0
12
12
0
12
0
0
0
89
0
0
23
% S
% Thr:
0
0
12
0
23
0
0
67
0
0
0
0
0
0
67
% T
% Val:
0
0
12
12
0
0
12
0
0
12
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
78
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _