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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK2
All Species:
16.36
Human Site:
Y319
Identified Species:
45
UniProt:
P78362
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78362
NP_872633.1
688
77543
Y319
S
N
D
Q
D
G
E
Y
C
P
E
V
K
L
K
Chimpanzee
Pan troglodytes
XP_001160812
687
77411
Y318
S
N
D
Q
D
G
E
Y
C
P
E
V
K
L
K
Rhesus Macaque
Macaca mulatta
XP_001088614
687
77455
Y318
S
N
D
Q
D
G
E
Y
C
P
E
V
K
L
K
Dog
Lupus familis
XP_849273
686
77402
Y317
S
N
E
Q
D
D
E
Y
R
P
E
G
K
L
K
Cat
Felis silvestris
Mouse
Mus musculus
O54781
681
76738
Y317
S
G
E
Q
D
G
E
Y
Q
P
E
V
T
L
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508534
693
78060
D322
E
Q
E
E
A
A
T
D
C
P
G
P
K
L
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001165329
695
78154
G315
L
N
E
Q
D
L
E
G
H
P
E
A
K
M
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
G374
S
D
S
P
G
G
G
G
G
G
H
S
D
S
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
I384
R
R
P
R
R
H
T
I
I
T
G
S
Q
P
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
95.6
N.A.
93.9
N.A.
N.A.
87.8
N.A.
80.7
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
99.4
99.2
96.5
N.A.
95.4
N.A.
N.A.
91.9
N.A.
87.4
N.A.
N.A.
N.A.
N.A.
36
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
73.3
N.A.
N.A.
33.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
N.A.
N.A.
46.6
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
45
0
0
0
0
0
0
% C
% Asp:
0
12
34
0
67
12
0
12
0
0
0
0
12
0
0
% D
% Glu:
12
0
45
12
0
0
67
0
0
0
67
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
12
0
0
12
56
12
23
12
12
23
12
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
12
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
78
% K
% Leu:
12
0
0
0
0
12
0
0
0
0
0
0
0
67
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
12
0
0
0
0
0
78
0
12
0
12
0
% P
% Gln:
0
12
0
67
0
0
0
0
12
0
0
0
12
0
0
% Q
% Arg:
12
12
0
12
12
0
0
0
12
0
0
0
0
0
0
% R
% Ser:
67
0
12
0
0
0
0
0
0
0
0
23
0
12
0
% S
% Thr:
0
0
0
0
0
0
23
0
0
12
0
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
45
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _