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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA4 All Species: 10.61
Human Site: S1317 Identified Species: 21.21
UniProt: P78363 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78363 NP_000341.2 2273 255944 S1317 A G Q T P Q D S N V C S P G A
Chimpanzee Pan troglodytes XP_001152577 2346 264166 S1390 T G Q T P Q D S N V C S P G A
Rhesus Macaque Macaca mulatta XP_001093459 2148 234326 E1198 E P A G S A P E T Q A L Q G S
Dog Lupus familis XP_538773 2261 253895 D1288 C L R P F T E D D A I D P N D
Cat Felis silvestris
Mouse Mus musculus O35600 2310 260191 P1317 L R Q Y A Q A P H T C S P G Q
Rat Rattus norvegicus Q7TNJ2 2170 237702 V1209 N G E L A K L V L D P Q A P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 S1301 A S V D P N D S D V D P E S R
Chicken Gallus gallus XP_422330 2276 256293 T1314 A E Q T P V E T N D T S R M P
Frog Xenopus laevis NP_001089022 2363 267334 T1393 E S S I R K D T H H C V A D K
Zebra Danio Brachydanio rerio XP_683123 2330 265308 G1367 G L A E D A N G V G A S L E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 A833 P L F Q A L E A I Q D R N Y R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 T1011 H P D Q K S I T L T T A Y F N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 45.2 51 N.A. 87 45.4 N.A. 50.9 71.6 66.6 63.4 N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: 100 96.3 62 67.9 N.A. 92.8 63.5 N.A. 67.7 83.4 79.7 76.8 N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: 100 93.3 6.6 6.6 N.A. 40 6.6 N.A. 33.3 40 13.3 6.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 93.3 13.3 26.6 N.A. 46.6 20 N.A. 40 53.3 33.3 20 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 17 0 25 17 9 9 0 9 17 9 17 0 17 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % C
% Asp: 0 0 9 9 9 0 34 9 17 17 17 9 0 9 9 % D
% Glu: 17 9 9 9 0 0 25 9 0 0 0 0 9 9 0 % E
% Phe: 0 0 9 0 9 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 9 25 0 9 0 0 0 9 0 9 0 0 0 34 0 % G
% His: 9 0 0 0 0 0 0 0 17 9 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 9 0 9 0 9 0 0 0 0 % I
% Lys: 0 0 0 0 9 17 0 0 0 0 0 0 0 0 17 % K
% Leu: 9 25 0 9 0 9 9 0 17 0 0 9 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 9 0 0 0 0 9 9 0 25 0 0 0 9 9 9 % N
% Pro: 9 17 0 9 34 0 9 9 0 0 9 9 34 9 9 % P
% Gln: 0 0 34 17 0 25 0 0 0 17 0 9 9 0 9 % Q
% Arg: 0 9 9 0 9 0 0 0 0 0 0 9 9 0 17 % R
% Ser: 0 17 9 0 9 9 0 25 0 0 0 42 0 9 17 % S
% Thr: 9 0 0 25 0 9 0 25 9 17 17 0 0 0 0 % T
% Val: 0 0 9 0 0 9 0 9 9 25 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _