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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA4
All Species:
16.67
Human Site:
S217
Identified Species:
33.33
UniProt:
P78363
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78363
NP_000341.2
2273
255944
S217
L
E
R
F
I
I
F
S
Q
R
R
G
A
K
T
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
S290
L
E
R
F
I
I
F
S
Q
R
R
G
A
Q
T
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
A187
L
Q
S
L
L
E
A
A
E
D
L
A
Q
E
I
Dog
Lupus familis
XP_538773
2261
253895
E202
C
S
G
S
K
L
E
E
V
I
Q
L
G
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35600
2310
260191
S217
L
Q
R
F
I
I
F
S
Q
R
R
G
A
Q
T
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
L204
L
V
E
L
R
A
L
L
R
R
P
R
G
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
N207
L
T
E
F
V
K
I
N
D
Q
A
L
A
E
L
Chicken
Gallus gallus
XP_422330
2276
256293
S217
L
D
R
F
I
I
F
S
S
R
R
G
L
P
S
Frog
Xenopus laevis
NP_001089022
2363
267334
S217
L
E
R
F
I
I
F
S
S
R
R
G
M
Q
T
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
P217
L
E
Q
F
L
I
F
P
S
R
G
G
M
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
F8
M
G
S
S
K
R
Q
F
K
A
M
L
R
K
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
45.2
51
N.A.
87
45.4
N.A.
50.9
71.6
66.6
63.4
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
96.3
62
67.9
N.A.
92.8
63.5
N.A.
67.7
83.4
79.7
76.8
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
93.3
6.6
0
N.A.
86.6
13.3
N.A.
20
66.6
80
46.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
40
20
N.A.
100
20
N.A.
46.6
80
86.6
60
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
9
0
9
9
9
34
0
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
9
9
0
0
0
0
0
% D
% Glu:
0
34
17
0
0
9
9
9
9
0
0
0
0
25
0
% E
% Phe:
0
0
0
59
0
0
50
9
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
0
0
0
9
50
17
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
42
50
9
0
0
9
0
0
0
0
9
% I
% Lys:
0
0
0
0
17
9
0
0
9
0
0
0
0
17
0
% K
% Leu:
75
0
0
17
17
9
9
9
0
0
9
25
9
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
9
0
17
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
9
0
0
9
0
% P
% Gln:
0
17
9
0
0
0
9
0
25
9
9
0
9
25
9
% Q
% Arg:
0
0
42
0
9
9
0
0
9
59
42
9
9
0
0
% R
% Ser:
0
9
17
17
0
0
0
42
25
0
0
0
0
9
9
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
34
% T
% Val:
0
9
0
0
9
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _