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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA4
All Species:
11.82
Human Site:
T1186
Identified Species:
23.64
UniProt:
P78363
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78363
NP_000341.2
2273
255944
T1186
C
S
S
K
G
F
S
T
T
C
P
A
H
V
D
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
T1259
C
S
S
K
G
F
S
T
T
C
P
A
H
V
D
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
A1114
G
A
H
D
G
S
F
A
T
L
F
Q
E
L
D
Dog
Lupus familis
XP_538773
2261
253895
S1157
S
Y
L
K
K
E
D
S
V
S
Q
S
S
S
D
Cat
Felis silvestris
Mouse
Mus musculus
O35600
2310
260191
T1186
C
T
S
K
G
F
S
T
R
C
P
T
R
V
D
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
Y1124
E
L
V
L
A
L
P
Y
A
G
A
L
D
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
S1161
S
Y
L
K
K
E
D
S
V
S
Q
S
S
S
D
Chicken
Gallus gallus
XP_422330
2276
256293
S1185
Q
C
S
C
S
C
S
S
C
A
L
M
D
K
E
Frog
Xenopus laevis
NP_001089022
2363
267334
A1254
S
D
C
S
C
P
C
A
S
C
T
P
K
A
K
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
C1237
C
S
C
T
C
S
T
C
T
R
Y
K
E
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
M750
L
G
D
W
V
F
I
M
S
H
G
K
L
V
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
K928
V
I
I
T
S
V
A
K
A
F
R
L
I
V
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
45.2
51
N.A.
87
45.4
N.A.
50.9
71.6
66.6
63.4
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
96.3
62
67.9
N.A.
92.8
63.5
N.A.
67.7
83.4
79.7
76.8
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
100
20
13.3
N.A.
73.3
0
N.A.
13.3
13.3
6.6
20
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
33.3
26.6
N.A.
80
0
N.A.
26.6
26.6
13.3
26.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
9
17
17
9
9
17
0
9
17
% A
% Cys:
34
9
17
9
17
9
9
9
9
34
0
0
0
0
0
% C
% Asp:
0
9
9
9
0
0
17
0
0
0
0
0
17
0
50
% D
% Glu:
9
0
0
0
0
17
0
0
0
0
0
0
17
9
9
% E
% Phe:
0
0
0
0
0
34
9
0
0
9
9
0
0
0
0
% F
% Gly:
9
9
0
0
34
0
0
0
0
9
9
0
0
9
0
% G
% His:
0
0
9
0
0
0
0
0
0
9
0
0
17
0
0
% H
% Ile:
0
9
9
0
0
0
9
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
42
17
0
0
9
0
0
0
17
9
9
9
% K
% Leu:
9
9
17
9
0
9
0
0
0
9
9
17
9
9
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
9
0
0
0
25
9
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
17
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
9
9
0
9
0
0
% R
% Ser:
25
25
34
9
17
17
34
25
17
17
0
17
17
17
17
% S
% Thr:
0
9
0
17
0
0
9
25
34
0
9
9
0
0
0
% T
% Val:
9
0
9
0
9
9
0
0
17
0
0
0
0
42
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
9
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _