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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA4 All Species: 13.94
Human Site: T1935 Identified Species: 27.88
UniProt: P78363 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78363 NP_000341.2 2273 255944 T1935 I I T G G N K T D I L R L H E
Chimpanzee Pan troglodytes XP_001152577 2346 264166 T2008 I I T G G N K T D I L R L H E
Rhesus Macaque Macaca mulatta XP_001093459 2148 234326 G1792 V V R G A T Q G D V L V L R N
Dog Lupus familis XP_538773 2261 253895 N1909 I L D G G G Q N D I L E I K E
Cat Felis silvestris
Mouse Mus musculus O35600 2310 260191 T1934 V M S G G N K T D I L K L N E
Rat Rattus norvegicus Q7TNJ2 2170 237702 G1815 V T K G A T Q G D V L V L R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 N1914 I L D G G G Q N D I L E I K E
Chicken Gallus gallus XP_422330 2276 256293 T1928 I L N G G N K T N I L E L Q E
Frog Xenopus laevis NP_001089022 2363 267334 N2014 V M K G G G K N D I L K L K E
Zebra Danio Brachydanio rerio XP_683123 2330 265308 N1980 I Y K G G N K N D I L L I R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 A1393 K T F G R F T A V N E L C L A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 T1571 H R I D N V V T E K L V E F D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 45.2 51 N.A. 87 45.4 N.A. 50.9 71.6 66.6 63.4 N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: 100 96.3 62 67.9 N.A. 92.8 63.5 N.A. 67.7 83.4 79.7 76.8 N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: 100 100 26.6 46.6 N.A. 66.6 26.6 N.A. 46.6 66.6 53.3 53.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 53.3 66.6 N.A. 100 53.3 N.A. 66.6 80 73.3 66.6 N.A. N.A. N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 0 0 9 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 17 9 0 0 0 0 75 0 0 0 0 0 25 % D
% Glu: 0 0 0 0 0 0 0 0 9 0 9 25 9 0 59 % E
% Phe: 0 0 9 0 0 9 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 92 67 25 0 17 0 0 0 0 0 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % H
% Ile: 50 17 9 0 0 0 0 0 0 67 0 0 25 0 0 % I
% Lys: 9 0 25 0 0 0 50 0 0 9 0 17 0 25 0 % K
% Leu: 0 25 0 0 0 0 0 0 0 0 92 17 59 9 0 % L
% Met: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 9 42 0 34 9 9 0 0 0 9 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 34 0 0 0 0 0 0 9 0 % Q
% Arg: 0 9 9 0 9 0 0 0 0 0 0 17 0 25 0 % R
% Ser: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 17 17 0 0 17 9 42 0 0 0 0 0 0 0 % T
% Val: 34 9 0 0 0 9 9 0 9 17 0 25 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _