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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA4 All Species: 40.91
Human Site: T1981 Identified Species: 81.82
UniProt: P78363 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78363 NP_000341.2 2273 255944 T1981 N G A G K T T T F K M L T G D
Chimpanzee Pan troglodytes XP_001152577 2346 264166 T2054 N G A G K T T T F K M L T G D
Rhesus Macaque Macaca mulatta XP_001093459 2148 234326 T1838 N G A G K T S T F R M V T G D
Dog Lupus familis XP_538773 2261 253895 T1955 N G A G K S S T F K M L T G D
Cat Felis silvestris
Mouse Mus musculus O35600 2310 260191 T1980 N G A G K T T T F K M L T G D
Rat Rattus norvegicus Q7TNJ2 2170 237702 T1861 N G A G K T S T F R M V T G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 T1960 N G A G K S S T F K M L T G D
Chicken Gallus gallus XP_422330 2276 256293 T1974 N G A G K T T T F K M L T G D
Frog Xenopus laevis NP_001089022 2363 267334 T2060 N G A G K T T T F K M L T G D
Zebra Danio Brachydanio rerio XP_683123 2330 265308 T2026 N G A G K T T T F K M L T G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 Q1427 T F N I L T G Q S F A S S G E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 I1605 L S V A I A M I G D P P I V I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 45.2 51 N.A. 87 45.4 N.A. 50.9 71.6 66.6 63.4 N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: 100 96.3 62 67.9 N.A. 92.8 63.5 N.A. 67.7 83.4 79.7 76.8 N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: 100 100 80 86.6 N.A. 100 80 N.A. 86.6 100 100 100 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 84 9 0 9 0 0 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 84 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 9 0 0 0 0 0 0 84 9 0 0 0 0 0 % F
% Gly: 0 84 0 84 0 0 9 0 9 0 0 0 0 92 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 9 0 0 9 0 0 0 0 9 0 9 % I
% Lys: 0 0 0 0 84 0 0 0 0 67 0 0 0 0 0 % K
% Leu: 9 0 0 0 9 0 0 0 0 0 0 67 0 0 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 84 0 0 0 0 % M
% Asn: 84 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % R
% Ser: 0 9 0 0 0 17 34 0 9 0 0 9 9 0 0 % S
% Thr: 9 0 0 0 0 75 50 84 0 0 0 0 84 0 0 % T
% Val: 0 0 9 0 0 0 0 0 0 0 0 17 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _