Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA4 All Species: 23.64
Human Site: T367 Identified Species: 47.27
UniProt: P78363 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78363 NP_000341.2 2273 255944 T367 Y S Y D R R T T S F C N A L I
Chimpanzee Pan troglodytes XP_001152577 2346 264166 T440 Y S Y D R R T T S F C N A L I
Rhesus Macaque Macaca mulatta XP_001093459 2148 234326 T337 V L G P R I F T F M N D S S N
Dog Lupus familis XP_538773 2261 253895 T352 S F Y D N S T T P Y C N D L M
Cat Felis silvestris
Mouse Mus musculus O35600 2310 260191 T367 Y S Y D K R T T S F C N S L I
Rat Rattus norvegicus Q7TNJ2 2170 237702 T354 K L L D V E G T G W Q Q Q T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516009 2266 254238 T357 N F Y D N S T T P Y C N D L M
Chicken Gallus gallus XP_422330 2276 256293 P367 L Y D N T T T P F C N E L I Q
Frog Xenopus laevis NP_001089022 2363 267334 T367 Y L Y D K T T T P F C N A L I
Zebra Danio Brachydanio rerio XP_683123 2330 265308 T367 Y I Y D K T A T P F C N A L M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 P158 V V F H E Q G P H L F D Y S I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 45.2 51 N.A. 87 45.4 N.A. 50.9 71.6 66.6 63.4 N.A. N.A. N.A. 23.7 N.A.
Protein Similarity: 100 96.3 62 67.9 N.A. 92.8 63.5 N.A. 67.7 83.4 79.7 76.8 N.A. N.A. N.A. 42.1 N.A.
P-Site Identity: 100 100 13.3 46.6 N.A. 86.6 13.3 N.A. 46.6 6.6 73.3 60 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 26.6 60 N.A. 100 20 N.A. 60 20 80 73.3 N.A. N.A. N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 37.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 0 0 0 0 34 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 59 0 0 0 0 % C
% Asp: 0 0 9 67 0 0 0 0 0 0 0 17 17 0 0 % D
% Glu: 0 0 0 0 9 9 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 17 9 0 0 0 9 0 17 42 9 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 17 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 9 0 0 0 0 0 0 0 9 42 % I
% Lys: 9 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 25 9 0 0 0 0 0 0 9 0 0 9 59 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 25 % M
% Asn: 9 0 0 9 17 0 0 0 0 0 17 59 0 0 9 % N
% Pro: 0 0 0 9 0 0 0 17 34 0 0 0 0 0 9 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 9 9 9 0 9 % Q
% Arg: 0 0 0 0 25 25 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 25 0 0 0 17 0 0 25 0 0 0 17 17 0 % S
% Thr: 0 0 0 0 9 25 59 75 0 0 0 0 0 9 0 % T
% Val: 17 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 42 9 59 0 0 0 0 0 0 17 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _