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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA4
All Species:
30.3
Human Site:
Y1947
Identified Species:
60.61
UniProt:
P78363
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78363
NP_000341.2
2273
255944
Y1947
L
H
E
L
T
K
I
Y
P
G
T
S
S
P
A
Chimpanzee
Pan troglodytes
XP_001152577
2346
264166
Y2020
L
H
E
L
T
K
I
Y
P
G
T
S
S
P
A
Rhesus Macaque
Macaca mulatta
XP_001093459
2148
234326
Y1804
L
R
N
L
T
K
V
Y
H
G
Q
R
M
P
A
Dog
Lupus familis
XP_538773
2261
253895
Y1921
I
K
E
L
T
K
I
Y
R
R
K
R
K
P
A
Cat
Felis silvestris
Mouse
Mus musculus
O35600
2310
260191
Y1946
L
N
E
L
T
K
V
Y
S
G
S
S
S
P
A
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
Y1827
L
R
D
L
T
K
V
Y
R
G
Q
R
S
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
Y1926
I
K
E
L
T
K
V
Y
R
M
K
R
K
P
A
Chicken
Gallus gallus
XP_422330
2276
256293
Y1940
L
Q
E
L
T
K
I
Y
A
G
R
H
K
P
A
Frog
Xenopus laevis
NP_001089022
2363
267334
Y2026
L
K
E
L
T
K
T
Y
P
G
K
Q
S
P
A
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
Y1992
I
R
D
L
S
K
T
Y
R
R
R
K
R
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
E1405
C
L
A
V
D
Q
K
E
C
F
G
L
L
G
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
S1583
E
F
D
L
L
K
H
S
H
K
P
S
F
T
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
45.2
51
N.A.
87
45.4
N.A.
50.9
71.6
66.6
63.4
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
100
96.3
62
67.9
N.A.
92.8
63.5
N.A.
67.7
83.4
79.7
76.8
N.A.
N.A.
N.A.
42.1
N.A.
P-Site Identity:
100
100
53.3
53.3
N.A.
73.3
60
N.A.
46.6
66.6
73.3
33.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
60
60
N.A.
93.3
73.3
N.A.
60
66.6
73.3
53.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
84
% A
% Cys:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
25
0
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
59
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
9
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
59
9
0
0
9
0
% G
% His:
0
17
0
0
0
0
9
0
17
0
0
9
0
0
0
% H
% Ile:
25
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% I
% Lys:
0
25
0
0
0
92
9
0
0
9
25
9
25
0
0
% K
% Leu:
59
9
0
92
9
0
0
0
0
0
0
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% M
% Asn:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
25
0
9
0
0
84
0
% P
% Gln:
0
9
0
0
0
9
0
0
0
0
17
9
0
0
0
% Q
% Arg:
0
25
0
0
0
0
0
0
34
17
17
34
9
0
0
% R
% Ser:
0
0
0
0
9
0
0
9
9
0
9
34
42
0
0
% S
% Thr:
0
0
0
0
75
0
17
0
0
0
17
0
0
9
0
% T
% Val:
0
0
0
9
0
0
34
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _