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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX3-2
All Species:
13.64
Human Site:
S303
Identified Species:
33.33
UniProt:
P78367
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78367
NP_001180.1
333
34814
S303
G
E
V
L
R
P
P
S
L
L
P
L
Q
P
S
Chimpanzee
Pan troglodytes
XP_001159503
229
26021
F200
P
A
L
K
E
E
A
F
S
R
A
S
L
V
S
Rhesus Macaque
Macaca mulatta
XP_001098720
333
34915
S303
G
E
V
L
R
P
P
S
L
L
P
L
Q
P
S
Dog
Lupus familis
XP_545940
333
34529
S303
G
E
V
L
R
P
P
S
L
L
P
L
Q
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P97503
333
35174
S303
G
E
V
L
R
P
P
S
L
L
P
L
Q
P
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507333
521
57733
D474
K
R
K
Q
L
T
S
D
L
G
D
L
D
P
N
Chicken
Gallus gallus
Frog
Xenopus laevis
P70061
329
35981
L299
G
E
V
L
H
P
S
L
L
P
L
Q
A
P
Y
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
V268
S
T
N
T
A
G
N
V
P
V
S
Q
P
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120208
356
41090
I304
G
Q
M
S
A
P
Q
I
H
P
A
N
K
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26656
405
44721
N370
G
S
S
L
H
S
P
N
I
L
P
F
P
M
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.2
97.5
90.3
N.A.
84.6
N.A.
N.A.
29.7
N.A.
44.7
26.7
N.A.
N.A.
27.8
N.A.
26.1
Protein Similarity:
100
45.6
97.9
91.8
N.A.
87
N.A.
N.A.
37.8
N.A.
51.6
37.5
N.A.
N.A.
42.1
N.A.
39
P-Site Identity:
100
6.6
100
100
N.A.
100
N.A.
N.A.
20
N.A.
46.6
0
N.A.
N.A.
13.3
N.A.
33.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
N.A.
N.A.
26.6
N.A.
46.6
6.6
N.A.
N.A.
33.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
20
0
10
0
0
0
20
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% D
% Glu:
0
50
0
0
10
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
70
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
20
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% I
% Lys:
10
0
10
10
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
10
60
10
0
0
10
60
50
10
50
10
10
20
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
0
10
10
0
0
0
10
0
0
10
% N
% Pro:
10
0
0
0
0
60
50
0
10
20
50
0
20
60
10
% P
% Gln:
0
10
0
10
0
0
10
0
0
0
0
20
40
0
0
% Q
% Arg:
0
10
0
0
40
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
10
10
10
10
0
10
20
40
10
0
10
10
0
0
50
% S
% Thr:
0
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
50
0
0
0
0
10
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _