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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX3-2
All Species:
4.55
Human Site:
T162
Identified Species:
11.11
UniProt:
P78367
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78367
NP_001180.1
333
34814
T162
S
G
D
R
S
P
R
T
E
D
D
G
V
G
P
Chimpanzee
Pan troglodytes
XP_001159503
229
26021
Q72
G
R
R
R
A
G
A
Q
N
D
Q
L
S
T
G
Rhesus Macaque
Macaca mulatta
XP_001098720
333
34915
T162
S
G
D
R
S
P
R
T
E
D
D
G
V
G
P
Dog
Lupus familis
XP_545940
333
34529
A164
S
G
D
R
S
P
R
A
E
D
D
A
V
G
P
Cat
Felis silvestris
Mouse
Mus musculus
P97503
333
35174
G162
S
G
D
H
S
P
R
G
E
D
D
S
V
T
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507333
521
57733
V194
S
E
F
Q
A
W
R
V
I
P
S
P
P
E
P
Chicken
Gallus gallus
Frog
Xenopus laevis
P70061
329
35981
K159
R
P
L
E
A
R
A
K
G
E
D
E
E
E
T
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
E140
S
G
D
E
I
V
L
E
E
G
D
T
E
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120208
356
41090
L160
L
L
A
Q
T
L
K
L
T
S
T
Q
V
K
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26656
405
44721
L150
L
H
I
P
S
A
A
L
P
F
S
H
L
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.2
97.5
90.3
N.A.
84.6
N.A.
N.A.
29.7
N.A.
44.7
26.7
N.A.
N.A.
27.8
N.A.
26.1
Protein Similarity:
100
45.6
97.9
91.8
N.A.
87
N.A.
N.A.
37.8
N.A.
51.6
37.5
N.A.
N.A.
42.1
N.A.
39
P-Site Identity:
100
13.3
100
86.6
N.A.
73.3
N.A.
N.A.
20
N.A.
6.6
33.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
20
100
86.6
N.A.
73.3
N.A.
N.A.
33.3
N.A.
20
33.3
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
30
10
30
10
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
0
0
0
0
0
0
50
60
0
0
10
0
% D
% Glu:
0
10
0
20
0
0
0
10
50
10
0
10
20
20
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
50
0
0
0
10
0
10
10
10
0
20
0
30
20
% G
% His:
0
10
0
10
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
10
0
10
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
0
0
0
10
0
% K
% Leu:
20
10
10
0
0
10
10
20
0
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
10
0
10
0
40
0
0
10
10
0
10
10
0
50
% P
% Gln:
0
0
0
20
0
0
0
10
0
0
10
10
0
0
0
% Q
% Arg:
10
10
10
40
0
10
50
0
0
0
0
0
0
0
0
% R
% Ser:
60
0
0
0
50
0
0
0
0
10
20
10
10
0
0
% S
% Thr:
0
0
0
0
10
0
0
20
10
0
10
10
0
20
10
% T
% Val:
0
0
0
0
0
10
0
10
0
0
0
0
50
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _