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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKX3-2 All Species: 20
Human Site: Y293 Identified Species: 48.89
UniProt: P78367 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78367 NP_001180.1 333 34814 Y293 V R D D Q R Q Y L P G E V L R
Chimpanzee Pan troglodytes XP_001159503 229 26021 S190 L G D L E K H S S L P A L K E
Rhesus Macaque Macaca mulatta XP_001098720 333 34915 Y293 V R D D Q R Q Y L P G E V L R
Dog Lupus familis XP_545940 333 34529 Y293 V R D D Q R Q Y L P G E V L R
Cat Felis silvestris
Mouse Mus musculus P97503 333 35174 Y293 V R D D Q R L Y L P G E V L R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507333 521 57733 Y464 I W F Q N R R Y K T K R K Q L
Chicken Gallus gallus
Frog Xenopus laevis P70061 329 35981 Y289 V R D D Q R Q Y H P G E V L H
Zebra Danio Brachydanio rerio Q504H8 297 33069 A258 I L Y H E N S A S E S T N T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120208 356 41090 Q294 L P L R G S G Q L P G Q M S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26656 405 44721 P360 I L Y H E N H P T T G S S L H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.2 97.5 90.3 N.A. 84.6 N.A. N.A. 29.7 N.A. 44.7 26.7 N.A. N.A. 27.8 N.A. 26.1
Protein Similarity: 100 45.6 97.9 91.8 N.A. 87 N.A. N.A. 37.8 N.A. 51.6 37.5 N.A. N.A. 42.1 N.A. 39
P-Site Identity: 100 6.6 100 100 N.A. 93.3 N.A. N.A. 13.3 N.A. 86.6 0 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 100 33.3 100 100 N.A. 93.3 N.A. N.A. 26.6 N.A. 86.6 13.3 N.A. N.A. 40 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 60 50 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 30 0 0 0 0 10 0 50 0 0 10 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 10 0 10 0 0 0 70 0 0 0 0 % G
% His: 0 0 0 20 0 0 20 0 10 0 0 0 0 0 20 % H
% Ile: 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 10 0 10 0 10 10 0 % K
% Leu: 20 20 10 10 0 0 10 0 50 10 0 0 10 60 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 10 20 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 10 0 0 0 0 0 10 0 60 10 0 0 0 0 % P
% Gln: 0 0 0 10 50 0 40 10 0 0 0 10 0 10 0 % Q
% Arg: 0 50 0 10 0 60 10 0 0 0 0 10 0 0 40 % R
% Ser: 0 0 0 0 0 10 10 10 20 0 10 10 10 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 20 0 10 0 10 0 % T
% Val: 50 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 20 0 0 0 0 60 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _