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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC35B1 All Species: 22.72
Human Site: S6 Identified Species: 41.65
UniProt: P78383 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78383 NP_005818.1 322 35760 S6 _ _ M A S S S S L V P D R L R
Chimpanzee Pan troglodytes XP_001156965 504 55299 S154 R L M A S S S S L V P D R L R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537671 360 39538 S44 R L M A A S S S L V P D R L R
Cat Felis silvestris
Mouse Mus musculus P97858 322 35864 S6 _ _ M A A S R S L V P D R L R
Rat Rattus norvegicus Q6V7K3 322 35798 S6 _ _ M A A S R S L V P D R L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8AWB6 325 36035 S9 G A N A G R R S R S P E R L R
Frog Xenopus laevis Q6GQ70 320 35333 A6 _ _ M S S A P A S G G L R L L
Zebra Danio Brachydanio rerio Q66HX0 329 36794 L12 K A A S K P S L W Q N E R V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDD7 338 37419 R8 M N L P E R S R F V I Y A V G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20787 364 40817 H13 I H S D C S V H M L P R H V K
Sea Urchin Strong. purpuratus XP_783979 316 34870 P6 _ _ M P G A Q P G S T G K L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_563949 331 36699 S6 _ _ M E S H G S G L R R V L L
Baker's Yeast Sacchar. cerevisiae Q12520 339 38057 S7 _ M A G S T S S L V I C A I G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.8 N.A. 87.7 N.A. 95.6 95.9 N.A. N.A. 87.3 80.7 72.3 N.A. 49.1 N.A. 23.8 58.7
Protein Similarity: 100 63.8 N.A. 88.8 N.A. 97.8 98.1 N.A. N.A. 92.6 90 84.8 N.A. 64.5 N.A. 42.8 73.6
P-Site Identity: 100 86.6 N.A. 80 N.A. 84.6 84.6 N.A. N.A. 40 30.7 20 N.A. 13.3 N.A. 13.3 15.3
P-Site Similarity: 100 86.6 N.A. 86.6 N.A. 92.3 92.3 N.A. N.A. 53.3 53.8 40 N.A. 26.6 N.A. 46.6 30.7
Percent
Protein Identity: N.A. N.A. N.A. 35.6 27.1 N.A.
Protein Similarity: N.A. N.A. N.A. 53.1 46.9 N.A.
P-Site Identity: N.A. N.A. N.A. 30.7 35.7 N.A.
P-Site Similarity: N.A. N.A. N.A. 38.4 50 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 16 47 24 16 0 8 0 0 0 0 16 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 39 0 0 0 % D
% Glu: 0 0 0 8 8 0 0 0 0 0 0 16 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 16 0 8 0 16 8 8 8 0 0 16 % G
% His: 0 8 0 0 0 8 0 8 0 0 0 0 8 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 16 0 0 8 0 % I
% Lys: 8 0 0 0 8 0 0 0 0 0 0 0 8 0 8 % K
% Leu: 0 16 8 0 0 0 0 8 47 16 0 8 0 70 24 % L
% Met: 8 8 62 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 16 0 8 8 8 0 0 54 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % Q
% Arg: 16 0 0 0 0 16 24 8 8 0 8 16 62 0 54 % R
% Ser: 0 0 8 16 39 47 47 62 8 16 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 54 0 0 8 24 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 54 47 0 0 0 0 0 0 0 0 0 0 0 0 0 % _