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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRAME
All Species:
13.94
Human Site:
T494
Identified Species:
43.81
UniProt:
P78395
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78395
NP_996836.1
509
57890
T494
C
P
H
C
G
D
R
T
F
Y
D
P
E
P
I
Chimpanzee
Pan troglodytes
XP_525643
509
58113
S494
C
P
H
C
G
D
R
S
F
Y
D
P
E
P
I
Rhesus Macaque
Macaca mulatta
XP_001090516
509
57751
T494
C
P
H
C
G
D
R
T
F
Y
D
P
E
P
I
Dog
Lupus familis
XP_534747
503
56957
T488
C
P
R
C
G
D
R
T
F
Y
D
P
E
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC16
493
54950
G484
L
W
T
T
D
I
Y
G
R
L
A
A
D
Y
F
Rat
Rattus norvegicus
Q569B5
493
54896
G484
L
W
T
T
D
I
Y
G
R
L
A
A
D
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q640Z9
509
57042
T496
R
M
D
M
V
W
T
T
D
M
Y
V
Q
R
T
Zebra Danio
Brachydanio rerio
Q1L8H0
526
59513
N488
G
V
Y
D
A
D
I
N
E
T
S
N
E
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
94.3
68.5
N.A.
26.9
27.1
N.A.
N.A.
N.A.
26.1
22.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98
96.6
79.9
N.A.
43.2
43.8
N.A.
N.A.
N.A.
41.4
40.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
93.3
N.A.
0
0
N.A.
N.A.
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
0
25
25
0
0
0
% A
% Cys:
50
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
13
25
63
0
0
13
0
50
0
25
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
13
0
0
0
63
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
25
% F
% Gly:
13
0
0
0
50
0
0
25
0
0
0
0
0
0
13
% G
% His:
0
0
38
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
25
13
0
0
0
0
0
0
0
50
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
0
0
0
0
0
0
0
0
25
0
0
0
13
0
% L
% Met:
0
13
0
13
0
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
0
% N
% Pro:
0
50
0
0
0
0
0
0
0
0
0
50
0
50
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% Q
% Arg:
13
0
13
0
0
0
50
0
25
0
0
0
0
13
0
% R
% Ser:
0
0
0
0
0
0
0
13
0
0
13
0
0
0
0
% S
% Thr:
0
0
25
25
0
0
13
50
0
13
0
0
0
0
13
% T
% Val:
0
13
0
0
13
0
0
0
0
0
0
13
0
0
0
% V
% Trp:
0
25
0
0
0
13
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
0
25
0
0
50
13
0
0
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _