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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNA1 All Species: 13.64
Human Site: S149 Identified Species: 25
UniProt: P78396 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78396 NP_001104515.1 465 52358 S149 L E Q G D R D S C S V R E G M
Chimpanzee Pan troglodytes XP_522658 465 52444 S149 L E Q G D R D S C S V R E G M
Rhesus Macaque Macaca mulatta XP_001084161 465 52702 S149 L E Q G D G D S C S G R E G M
Dog Lupus familis XP_534494 458 51447 S142 A E Q G D R D S C T G R E G M
Cat Felis silvestris
Mouse Mus musculus Q61456 421 47753 F114 S G K E G I I F E D V Y E V D
Rat Rattus norvegicus Q6AY13 421 47676 F114 P G R E G I V F E D V Y E V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511579 423 48197 Y116 T V G E Q V E Y G D V R E A E
Chicken Gallus gallus P43449 395 44062 D88 E R D E E A A D A P G L R A A
Frog Xenopus laevis P18606 418 46754 C111 T Y S V E I D C P S L G D E D
Zebra Danio Brachydanio rerio NP_997983 390 43948 V83 R V I E T A T V Q S V K S T F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P14785 491 56134 D141 Q K E L V D Y D L D S T P M S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999646 457 51232 I142 D T A L S L P I P Q A Q R I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FMH5 355 40937 K48 L P N L S N I K K S R K A T T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 95.6 82.3 N.A. 76.7 76.9 N.A. 67.7 44.2 53.5 48.3 N.A. 31.9 N.A. N.A. 40
Protein Similarity: 100 99.3 96.9 86.4 N.A. 82.8 81.9 N.A. 76.7 58 66.6 60.8 N.A. 47.2 N.A. N.A. 55.9
P-Site Identity: 100 100 86.6 80 N.A. 13.3 13.3 N.A. 20 0 13.3 13.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 86.6 86.6 N.A. 20 20 N.A. 26.6 6.6 33.3 20 N.A. 13.3 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 29.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 16 8 0 8 0 8 0 8 16 8 % A
% Cys: 0 0 0 0 0 0 0 8 31 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 31 8 39 16 0 31 0 0 8 0 24 % D
% Glu: 8 31 8 39 16 0 8 0 16 0 0 0 54 8 8 % E
% Phe: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 8 % F
% Gly: 0 16 8 31 16 8 0 0 8 0 24 8 0 31 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 24 16 8 0 0 0 0 0 8 0 % I
% Lys: 0 8 8 0 0 0 0 8 8 0 0 16 0 0 0 % K
% Leu: 31 0 0 24 0 8 0 0 8 0 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 31 % M
% Asn: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 0 0 0 8 0 16 8 0 0 8 0 8 % P
% Gln: 8 0 31 0 8 0 0 0 8 8 0 8 0 0 0 % Q
% Arg: 8 8 8 0 0 24 0 0 0 0 8 39 16 0 0 % R
% Ser: 8 0 8 0 16 0 0 31 0 47 8 0 8 0 8 % S
% Thr: 16 8 0 0 8 0 8 0 0 8 0 8 0 16 8 % T
% Val: 0 16 0 8 8 8 8 8 0 0 47 0 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 8 8 0 0 0 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _