KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNA1
All Species:
20.91
Human Site:
Y450
Identified Species:
38.33
UniProt:
P78396
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78396
NP_001104515.1
465
52358
Y450
E
K
Y
K
A
S
K
Y
L
C
V
S
L
M
E
Chimpanzee
Pan troglodytes
XP_522658
465
52444
Y450
E
K
Y
K
A
S
K
Y
L
C
V
S
L
M
E
Rhesus Macaque
Macaca mulatta
XP_001084161
465
52702
Y450
E
K
Y
K
A
S
K
Y
L
R
V
S
L
M
E
Dog
Lupus familis
XP_534494
458
51447
Y443
E
K
Y
K
A
S
K
Y
M
H
V
S
L
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61456
421
47753
S410
A
S
K
Y
L
H
V
S
L
M
E
P
P
V
V
Rat
Rattus norvegicus
Q6AY13
421
47676
S410
A
S
K
Y
L
H
V
S
L
M
E
P
P
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511579
423
48197
S412
A
P
K
Y
M
H
V
S
L
M
E
P
P
V
F
Chicken
Gallus gallus
P43449
395
44062
V384
K
S
T
K
Y
H
A
V
S
L
I
D
A
P
E
Frog
Xenopus laevis
P18606
418
46754
S407
T
T
K
Y
M
Q
V
S
L
L
E
M
P
S
I
Zebra Danio
Brachydanio rerio
NP_997983
390
43948
S379
S
S
K
Y
H
G
V
S
Q
L
E
P
V
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P14785
491
56134
Y442
E
K
Y
N
R
D
T
Y
K
K
V
A
M
M
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999646
457
51232
Y442
E
K
Y
K
S
Q
K
Y
S
G
A
S
M
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FMH5
355
40937
E344
A
T
M
P
V
S
P
E
L
P
L
T
V
F
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
95.6
82.3
N.A.
76.7
76.9
N.A.
67.7
44.2
53.5
48.3
N.A.
31.9
N.A.
N.A.
40
Protein Similarity:
100
99.3
96.9
86.4
N.A.
82.8
81.9
N.A.
76.7
58
66.6
60.8
N.A.
47.2
N.A.
N.A.
55.9
P-Site Identity:
100
100
93.3
86.6
N.A.
6.6
6.6
N.A.
6.6
13.3
6.6
0
N.A.
46.6
N.A.
N.A.
46.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
13.3
13.3
N.A.
13.3
26.6
6.6
6.6
N.A.
60
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
0
0
31
0
8
0
0
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% D
% Glu:
47
0
0
0
0
0
0
8
0
0
39
0
0
8
54
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
8
31
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
8
47
39
47
0
0
39
0
8
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
16
0
0
0
62
24
8
0
31
0
0
% L
% Met:
0
0
8
0
16
0
0
0
8
24
0
8
16
39
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
8
0
0
8
0
31
31
8
8
% P
% Gln:
0
0
0
0
0
16
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
31
0
0
8
39
0
39
16
0
0
39
0
8
0
% S
% Thr:
8
16
8
0
0
0
8
0
0
0
0
8
0
8
8
% T
% Val:
0
0
0
0
8
0
39
8
0
0
39
0
16
24
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
47
39
8
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _