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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAE1 All Species: 26.97
Human Site: S46 Identified Species: 42.38
UniProt: P78406 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78406 NP_001015885.1 368 40968 S46 D D S I G C L S F S P P T L P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001087530 390 43175 S46 D D S I G C L S F S P P T L P
Dog Lupus familis XP_543066 368 40993 S46 D D S I G C L S F S P P T L P
Cat Felis silvestris
Mouse Mus musculus Q8C570 368 40947 S46 D D S I G C L S F S P P T L P
Rat Rattus norvegicus Q3SWS8 368 40901 S46 D D S I G C L S F S P P T L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510132 368 40869 S46 D D S I G C L S F S P P T L P
Chicken Gallus gallus Q5R1S9 566 62559 V89 A S G G D D A V I L L W K L N
Frog Xenopus laevis NP_001091418 368 40883 S46 D D S I S C L S F S P P T L P
Zebra Danio Brachydanio rerio Q7ZWF0 368 41033 A46 D D S I S C L A F S P P T M P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611597 346 38599 N37 S P S T V Q K N F L V A G S W
Honey Bee Apis mellifera XP_392693 355 39405 L47 A S I P Q N F L V A G S W D C
Nematode Worm Caenorhab. elegans Q93454 373 41394 K49 E D T I Q V I K F S P T P Q D
Sea Urchin Strong. purpuratus XP_001203816 372 41730 A49 S S L R F S P A S I P N T F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38942 349 38249 V41 S P R A D I L V A T S W D N Q
Baker's Yeast Sacchar. cerevisiae P40066 365 40504 P46 I S D I A F S P Q Q D F M F S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 88.7 99.1 N.A. 98.6 98.3 N.A. 95.6 20.8 91.5 91 N.A. 65.2 67.6 51.4 68
Protein Similarity: 100 N.A. 90.2 99.7 N.A. 99.4 99.1 N.A. 97.8 33 96.1 96.7 N.A. 76 78.5 63 80.9
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 6.6 93.3 80 N.A. 13.3 0 33.3 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 6.6 93.3 93.3 N.A. 20 6.6 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. 50.8 41.5 N.A.
Protein Similarity: N.A. N.A. N.A. 65.2 58.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 7 7 0 7 14 7 7 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 54 0 0 0 0 0 0 0 0 7 % C
% Asp: 54 60 7 0 14 7 0 0 0 0 7 0 7 7 7 % D
% Glu: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 7 7 7 0 67 0 0 7 0 14 0 % F
% Gly: 0 0 7 7 40 0 0 0 0 0 7 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 7 67 0 7 7 0 7 7 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 7 7 0 0 0 0 7 0 0 % K
% Leu: 0 0 7 0 0 0 60 7 0 14 7 0 0 54 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % M
% Asn: 0 0 0 0 0 7 0 7 0 0 0 7 0 7 7 % N
% Pro: 0 14 0 7 0 0 7 7 0 0 67 54 7 0 54 % P
% Gln: 0 0 0 0 14 7 0 0 7 7 0 0 0 7 7 % Q
% Arg: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 20 27 60 0 14 7 7 47 7 60 7 7 0 7 7 % S
% Thr: 0 0 7 7 0 0 0 0 0 7 0 7 60 0 0 % T
% Val: 0 0 0 0 7 7 0 14 7 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 14 7 0 7 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _