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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRX5 All Species: 31.21
Human Site: S58 Identified Species: 68.67
UniProt: P78411 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78411 NP_005844.4 483 50361 S58 S T A F T A P S P G Y N S H L
Chimpanzee Pan troglodytes XP_510970 483 50329 S58 S T A F T A P S P G Y N S H L
Rhesus Macaque Macaca mulatta XP_001086980 483 50363 S58 S T A F T A P S P G Y N S H L
Dog Lupus familis XP_851198 483 50201 S58 S T A F T A P S P G Y N S H L
Cat Felis silvestris
Mouse Mus musculus Q9JKQ4 484 50737 S58 S T A F T A P S P G Y N S H L
Rat Rattus norvegicus NP_001025215 484 50649 S58 S T A F T A P S P G Y N S H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9YGS0 485 52755 Y86 G P Q G Y G N Y V T Y G T E A
Frog Xenopus laevis NP_001079223 474 51738 S58 S T A F T A S S A G F S S P L
Zebra Danio Brachydanio rerio NP_001038692 446 48355 S58 S T A F T S A S P G Y N S H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54269 693 73649 D171 P Y P S I G V D N S A F Y A P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93348 377 40765
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.9 97.7 N.A. 92.9 94.2 N.A. N.A. 32.3 61.9 65.8 N.A. 27.2 N.A. 27.7 N.A.
Protein Similarity: 100 100 99.3 98.9 N.A. 94.6 95.4 N.A. N.A. 43.9 70.5 72.8 N.A. 36.6 N.A. 38.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 66.6 86.6 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 13.3 80 93.3 N.A. 0 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 73 0 0 64 10 0 10 0 10 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 73 0 0 0 0 0 0 10 10 0 0 0 % F
% Gly: 10 0 0 10 0 19 0 0 0 73 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 10 0 0 64 0 0 0 % N
% Pro: 10 10 10 0 0 0 55 0 64 0 0 0 0 10 10 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 73 0 0 10 0 10 10 73 0 10 0 10 73 0 0 % S
% Thr: 0 73 0 0 73 0 0 0 0 10 0 0 10 0 0 % T
% Val: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 10 0 0 10 0 0 73 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _