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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRX6
All Species:
24.85
Human Site:
S245
Identified Species:
49.7
UniProt:
P78412
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78412
NP_077311.2
446
48240
S245
D
T
K
E
V
T
A
S
Q
E
A
R
G
L
R
Chimpanzee
Pan troglodytes
XP_001167355
444
48020
S245
D
T
K
E
V
T
A
S
Q
E
A
R
G
L
R
Rhesus Macaque
Macaca mulatta
XP_001087101
444
48073
S245
D
T
K
E
V
T
A
S
Q
E
A
R
G
L
R
Dog
Lupus familis
XP_544401
541
57810
S325
D
T
K
D
V
T
A
S
Q
E
A
P
G
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER75
438
47224
S241
D
T
K
D
A
T
A
S
Q
E
A
R
G
L
R
Rat
Rattus norvegicus
NP_001095883
443
47396
S242
D
T
K
D
A
T
A
S
Q
E
A
Q
G
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9YGS0
485
52755
G246
E
K
A
E
E
P
T
G
K
E
E
K
E
L
E
Frog
Xenopus laevis
NP_001154863
495
55384
E244
N
E
K
K
T
V
D
E
E
I
H
R
E
E
K
Zebra Danio
Brachydanio rerio
XP_691361
484
53120
S249
D
E
Q
D
L
Q
F
S
D
L
D
D
M
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24248
717
75403
A358
S
Q
G
S
V
S
L
A
K
D
E
T
K
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93348
377
40765
S208
D
M
N
R
P
S
S
S
T
S
I
N
S
E
R
Sea Urchin
Strong. purpuratus
NP_001123285
605
66354
E322
D
Y
R
R
R
S
G
E
L
L
A
E
H
H
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
94.1
66.3
N.A.
75.7
76.2
N.A.
N.A.
39.7
39.1
38.8
N.A.
26.3
N.A.
24.6
34
Protein Similarity:
100
98.4
95.7
69.8
N.A.
81.1
82.5
N.A.
N.A.
51.7
52.7
53.3
N.A.
35.8
N.A.
39.2
46.6
P-Site Identity:
100
100
100
86.6
N.A.
86.6
73.3
N.A.
N.A.
20
13.3
13.3
N.A.
6.6
N.A.
20
20
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
40
40
33.3
N.A.
33.3
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
17
0
50
9
0
0
59
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
0
34
0
0
9
0
9
9
9
9
0
0
9
% D
% Glu:
9
17
0
34
9
0
0
17
9
59
17
9
17
34
17
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
9
9
0
0
0
0
50
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
9
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% I
% Lys:
0
9
59
9
0
0
0
0
17
0
0
9
9
0
9
% K
% Leu:
0
0
0
0
9
0
9
0
9
17
0
0
0
59
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
9
9
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
9
9
0
0
9
0
0
50
0
0
9
0
0
9
% Q
% Arg:
0
0
9
17
9
0
0
0
0
0
0
42
0
0
59
% R
% Ser:
9
0
0
9
0
25
9
67
0
9
0
0
9
0
0
% S
% Thr:
0
50
0
0
9
50
9
0
9
0
0
9
0
0
0
% T
% Val:
0
0
0
0
42
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _