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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IRX6 All Species: 11.52
Human Site: S388 Identified Species: 23.03
UniProt: P78412 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P78412 NP_077311.2 446 48240 S388 I P G Q P P A S A R R L S V P
Chimpanzee Pan troglodytes XP_001167355 444 48020 S387 I P G Q P P A S A R R L S V P
Rhesus Macaque Macaca mulatta XP_001087101 444 48073 S387 I P G Q P P A S A R R L S V P
Dog Lupus familis XP_544401 541 57810 A466 I P G Q P P G A G G R P A V P
Cat Felis silvestris
Mouse Mus musculus Q9ER75 438 47224 I382 I P R Q P S S I R R L L V P R
Rat Rattus norvegicus NP_001095883 443 47396 V387 I P R Q P S S V R R L L V P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9YGS0 485 52755 P414 V D G V F H D P L F R H S T L
Frog Xenopus laevis NP_001154863 495 55384 D419 T S L R N W V D G V F H D P L
Zebra Danio Brachydanio rerio XP_691361 484 53120 T384 M Q G V R L P T V G A V Q C G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24248 717 75403 T580 Q Q G G T I H T T G S S S G P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93348 377 40765 A332 F Q L L A Q Q A A Q G Q Q L A
Sea Urchin Strong. purpuratus NP_001123285 605 66354 H468 P P G F P L H H S Q L A L A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 94.1 66.3 N.A. 75.7 76.2 N.A. N.A. 39.7 39.1 38.8 N.A. 26.3 N.A. 24.6 34
Protein Similarity: 100 98.4 95.7 69.8 N.A. 81.1 82.5 N.A. N.A. 51.7 52.7 53.3 N.A. 35.8 N.A. 39.2 46.6
P-Site Identity: 100 100 100 60 N.A. 40 40 N.A. N.A. 20 0 6.6 N.A. 20 N.A. 6.6 20
P-Site Similarity: 100 100 100 73.3 N.A. 46.6 46.6 N.A. N.A. 26.6 6.6 26.6 N.A. 26.6 N.A. 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 25 17 34 0 9 9 9 9 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 9 0 0 0 0 9 9 0 0 0 0 9 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 9 0 0 9 9 0 0 0 0 9 9 0 0 0 0 % F
% Gly: 0 0 67 9 0 0 9 0 17 25 9 0 0 9 9 % G
% His: 0 0 0 0 0 9 17 9 0 0 0 17 0 0 0 % H
% Ile: 50 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 17 9 0 17 0 0 9 0 25 42 9 9 17 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 59 0 0 59 34 9 9 0 0 0 9 0 25 42 % P
% Gln: 9 25 0 50 0 9 9 0 0 17 0 9 17 0 0 % Q
% Arg: 0 0 17 9 9 0 0 0 17 42 42 0 0 0 17 % R
% Ser: 0 9 0 0 0 17 17 25 9 0 9 9 42 0 0 % S
% Thr: 9 0 0 0 9 0 0 17 9 0 0 0 0 9 0 % T
% Val: 9 0 0 17 0 0 9 9 9 9 0 9 17 34 0 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _